Ethidium fluorescence assay. Part II. Enzymatic studies and DNA-protein interactions

A fluorescent complex between ethidium bromide and nucleic acids

1967 • 2,351 citations

SUPERCOILED CIRCULAR DNA-PROTEIN COMPLEX IN Escherichia coli : PURIFICATION AND INDUCED CONVERSION TO AN OPEN CIRCULAR DNA FORM

1969 • 1,847 citations

A New Method for the Large Scale Purification of Escherichia coli Deoxyribonucleic Acid-dependent Ribonucleic Acid Polymerase

1969 • 955 citations

Purification and Further Properties of Single‐Strand‐Specific Nuclease from Aspergillus oryzae

1973 • 862 citations

T4 Bacteriophage Gene 32: A Structural Protein in the Replication and Recombination of DNA

1970 • 793 citations

DEOXYRIBONUCLEIC ACID-DIRECTED SYNTHESIS OF RIBONUCLEIC ACID BY AN ENZYME FROM ESCHERICHIA COLI

1962 • 628 citations

The interaction of closed circular DNA with intercalative dyes

1968 • 627 citations

Generation of Superoxide Free Radical during the Autoxidation of Thiols

1974 • 558 citations

Mechanism of ethidium bromide fluorescence enhancement on binding to nucleic acids

1977 • 545 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1969 • 543 citations

Active Center of DNA Polymerase

1969 • 416 citations

The Deoxyribonucleases of Escherichia coli

1964 • 392 citations

Enzymatic Breakage and Joining of Deoxyribonucleic Acid

1968 • 382 citations

A Deoxyribonucleic Acid Phosphatase-Exonuclease from Escherichia coli

1964 • 332 citations

An Activity from Mammalian Cells That Untwists Superhelical DNA—A Possible Swivel For DNA Replication

1972 • 332 citations

Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA.

1977 • 265 citations

Isolation and Characterization of an Endonuclease from Escherichia coli Specific for Ribonucleic Acid in Ribonucleic Acid·Deoxyribonucleic Acid Hybrid Structures

1973 • 223 citations

Micrococcus luteus DNA gyrase: active components and a model for its supercoiling of DNA.

1978 • 206 citations

Isolation of Supercoiled Colicinogenic Factor E ₁ DNA Sensitive to Ribonuclease and Alkali

1972 • 160 citations

Enzymatic Joining of Polynucleotides

1970 • 156 citations

Purification and characterization of the DNA untwisting enzyme from rat liver

1976 • 134 citations

Native and denatured DNA, cross-linked and palindromic DNA and circular covalently-closed DNA analysed by a sensitive fluorometric procedure

1974 • 125 citations

The mechanism of DNA strand breakage by vitamin C and superoxide and the protective roles of catalase and superoxide dismutase

1976 • 123 citations

Oligodeoxyribonucleotide-primed Reactions Catalyzed by Calf Thymus Polymerase

1962 • 116 citations

Characterization of the Single‐Strand‐Specific Nuclease S₁ Activity on Double‐Stranded Supercoiled Polyoma DNA

1974 • 103 citations

Ethidium dimer: A new reagent for the fluorimetric determination of nucleic acids

1979 • 103 citations

DNA binding activity from cultured human fibrolasts that is specific for partially depurinated DNA and that inserts purines into apurinic sites.

1979 • 87 citations

The use of ethidium bromide-circular DNA complexes for the fluorometric analysis of breakage and joining of DNA

1971 • 83 citations

Biological sciences: mRNA is expected to form stable secondary structures

1974 • 81 citations

Isolation and Partial Characterisation of the Relaxation Protein from Nuclei of Cultured Mouse and Human Cells

1975 • 77 citations

Biosynthesis of Oligosaccharides and Polysaccharides in Plants

1969 • 77 citations

Properties of chromatin subunits from developing trout testis.

1975 • 70 citations

Purification and characterization of an omega protein from Micrococcus luteus.

1977 • 65 citations

Effect of incubation conditions on the nucleotide sequence of DNA products of unprimed DNA polymerase reactions

1970 • 64 citations

Partial purification of .omega. protein from calf thymus

1975 • 59 citations

Base-unpaired regions in supercoiled replicative form DNA of coliphage M13.

1977 • 35 citations

Studies on the mechanism of DNA cleavage by ethidium.

1976 • 35 citations

Enzymic synthesis of deoxyribonucleic acids with repeating sequences. New repeating trinucleotide deoxyribonucleic acid, d(T-C-C)_n·d(G-G-A)_n

1974 • 30 citations

Studies on polynucleotides

1970 • 29 citations

Purification and Characterization of an Endonuclease from Micrococcus luteus that Acts on Depurinated and Carcinogen‐Modified DNA

1978 • 29 citations

A Fluorescence Assay for DNA with Covalently Linked Complementary Sequences

1972 • 27 citations

A novel assay for endonucleases acting at apurinic sites and its use in measuring AP endonuclease activity in repair-deficient mutants of Saccharomyces cerevisiae

1979 • 20 citations

A rapid method for the measurement of the unwinding angle of intercalating agents and the superhelix density of circular DNAs

1978 • 19 citations

The isolation of a high molecular weight terminal deoxynucleotidyl transferase from calf thymus

1976 • 16 citations

The purification from Escherichia coli of a protein relaxing superhelical DNA

1976 • 16 citations

The purification and characterization of a DNA nicking–closing enzyme from Bacillus megaterium

1978 • 13 citations

In vitro synthesis and detection of deoxyribonucleic acids with covalently linked complementary sequences

1974 • 8 citations

DNA nicking–closing activity from salmon testis

1978 • 6 citations