Decreased striatal D2 dopamine receptor mRNA synthesis during aging

Cloning and expression of a rat D2 dopamine receptor cDNA

1988 • 1,125 citations

Effects of Age on Dopamine and Serotonin Receptors Measured by Positron Tomography in the Living Human Brain

1984 • 701 citations

Increased Life-Span of age -1 Mutants in Caenorhabditis elegans and Lower Gompertz Rate of Aging

1990 • 402 citations

DNA damage and rpair with age in individual human lymphocytes

1990 • 214 citations

Hereditary spherocytosis associated with deletion of human erythrocyte ankyrin gene on chromosome 8

1990 • 213 citations

Age-related Changes in the Nigrostriatum: A Behavioral and Biochemical Analysis

1978 • 197 citations

Reduced dopaminergic binding during aging in the rodent striatum

1980 • 197 citations

Senescent cells fail to express cdc2, cycA, and cycB in response to mitogen stimulation.

1991 • 183 citations

DNA damage metabolism and aging

1990 • 152 citations

Translation and a 42-nucleotide segment within the coding region of the mRNA encoded by the MAT alpha 1 gene are involved in promoting rapid mRNA decay in yeast.

1990 • 138 citations

Evidence for loss of brain [3H]spiroperidol and [3H]ADTN binding sites in rabbit brain with aging

1980 • 104 citations

Effect of aging on concentrations of D2-receptor-containing neurons in the rat striatum

1989 • 103 citations

Genes for human catecholamine-synthesizing enzymes

1991 • 98 citations

Dopamine receptor turnover rates in rat striatum are age-dependent.

1984 • 94 citations

A simplification of the nuclear run-off transcription assay.

1989 • 75 citations

Loss of D2 receptors during aging is partially due to decreased levels of mRNA

1991 • 75 citations

Age-related decreases in dopamine receptors in the caudate nucleus and putamen of the rhesus monkey (Macaca mulatta)

1987 • 67 citations

Induction of HSP70 Gene Expression by the Antiproliferative Prostaglandin PGA₂: A Growth-Dependent Response Mediated by Activation of Heat Shock Transcription Factor

1992 • 67 citations

Effect of aging on recovery of striatal dopamine receptors following n-ethoxycarbonyl-2-ethoxy-1, 2-dihydroquinoline (EEDQ) blockade

1984 • 63 citations

[3H]Haloperidol and [3H]spiroperidol binding in rat striatum during ageing

1978 • 57 citations

Induction of HSP70 gene expression by the antiproliferative prostaglandin PGA2: a growth-dependent response mediated by activation of heat shock transcription factor.

1992 • 44 citations

Post-transcriptional regulation of loss of rat striatal D2 dopamine receptor during aging

1992 • 43 citations

Developmental and age-related changes in the D2 dopamine receptor mRNA subtypes in rat brain

1992 • 42 citations

Effect of aging on striatal dopamine receptor subtype recovery following N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline blockade and relation to motor function in Wistar rats

1987 • 35 citations

Age-related variations in relative abundance of alternative spliced D2 receptor mRNAs in brain areas of two rat strains

1992 • 34 citations

Isolation and identification of aging-related cDNAs in the mouse

1990 • 14 citations