A Replication Cycle for Viroids and Other Small Infectious RNA's

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

1977 • 2,408 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

Electron microscopic evidence for the circular form of RNA in the cytoplasm of eukaryotic cells

1979 • 913 citations

In vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence

1981 • 877 citations

Nucleotide sequence and secondary structure of potato spindle tuber viroid

1978 • 504 citations

Purification and properties of the replicative intermediate of the RNA bacteriophage R17.

1966 • 497 citations

DNA Replication: The Rolling Circle Model

1968 • 435 citations

Mechanism of action of a yeast RNA ligase in tRNA splicing

1983 • 312 citations

Autocatalytic cyclization of an excised intervening sequence RNA is a cleavage–ligation reaction

1983 • 287 citations

Precise excision of intervening sequences from precursor tRNAs by a membrane-associated yeast endonuclease

1983 • 271 citations

Some yeast mitochondrial RNAs are circular

1980 • 229 citations

Replicative form of Encephalomyocarditis Virus Ribonucleic Acid

1963 • 219 citations

Nucleotide sequence from the genetic left end of bacteriophage T7 DNA to the beginning of gene 4

1981 • 183 citations

Splicing of yeast tRNA precursors: a two-stage reaction

1979 • 178 citations

Splicing of yeast tRNA precursors: structure of the reaction intermediates

1979 • 173 citations

Formation of a 2′-phosphomonoester, 3′,5′-phosphodiester linkage by a novel RNA ligase in wheat germ

1981 • 154 citations

Viroid RNAs of cadang-cadang disease of coconuts

1982 • 149 citations

DNA-dependent RNA polymerase II of plant origin transcribes viroid RNA into full-length copies

1981 • 147 citations

Virus-Specific Double-Stranded RNA in Poliovirus-Infected Cells

1964 • 134 citations

Longer-than-unit-length viroid minus strands are present in RNA from infected plants

1981 • 119 citations

RNA ligation via 2'-phosphomonoester, 3'5'-phosphodiester linkage: requirement of 2',3'-cyclic phosphate termini and involvement of a 5'-hydroxyl polynucleotide kinase.

1982 • 109 citations

RNA intermediates in potato spindle tuber viroid replication

1982 • 101 citations

Potato spindle tuber viroid. XII. An investigation of viroid RNA as a messenger for protein synthesis

1974 • 97 citations

RNA sequences complementary to citrus exocortis viroid in nucleic acid preparations from infected Gynura aurantiaca

1978 • 95 citations

Studies on encapsidated viroid-like RNA I. Characterization of velvet tobacco mottle virus

1981 • 93 citations

Purification and Characterization of the Circular and Linear Forms of Chrysanthemum Stunt Viroid

1980 • 89 citations

Circularization of linear viroid RNA via 2′-phosphomonoester, 3′, 5′-phosphodiester bonds by a novel type of RNA ligase from wheat germ andChlamydomonas

1982 • 85 citations

Cell-Free Circularization of Viroid Progeny RNA by an RNA Ligase from Wheat Germ

1982 • 80 citations

Determination of nucleotide sequences from double-stranded regions of HeLa cell nuclear RNA

1977 • 70 citations

Citrus exocortis viroid (CEV): Protein alterations in different hosts following viroid infection

1979 • 65 citations

Multimeric forms of satellite of tobacco ringspot virus RNA

1982 • 62 citations

Detection of complementary RNA intermediates of viroid replication by Northern blot hybridization

1981 • 58 citations

Oligomers of avocado sunblotch viroid are found in infected avocado leaves

1982 • 58 citations

Separation and infectivity of circular and linear forms of potato spindle tuber viroid.

1977 • 50 citations

Molecular cloning and characterization of potato spindle tuber viroid cDNA sequences

1980 • 48 citations

Satellite-like Properties of Small Circular RNA Molecules in Particles of Lucerne Transient Streak Virus

1983 • 45 citations

Tomato DNA contains no detectable regions complementary to potato spindle tuber viroid as assayed by solution and filter hybridization

1980 • 43 citations

Studies on encapsidated viroid-like RNA II. Purification and characterization of a viroid-like RNA associated with velvet tobacco mottle virus (VTMoV)

1981 • 41 citations

A New Model for Virus Ribonucleic Acid Replication

1965 • 40 citations

Tomato DNA contains no detectable regions complementary to potato spindle tuber viroid as assayed by Southern hybridization

1980 • 39 citations

Plant cell suspension cultures sustain long-term replication of potato spindle tuber viroid

1981 • 30 citations

Studies on encapsidated viroid-like RNA IV. requirement for infectivity and specificity of two RNA components from velvet tobacco mottle virus

1981 • 29 citations

Detection, isolation, and characterization of high molecular weight double-stranded RNAs in plants infected with velvet tobacco mottle virus

1983 • 29 citations

Nuclear DNA from uninfected or potato spindle tuber viroid-infected tomato plants contains no detectable sequences complementary to cloned double-stranded viroid cDNA.

1981 • 28 citations

In vitro transcription of viroid RNA into full-length copies by RNA-dependent RNA polymerase from healthy tomato leaf tissue

1982 • 25 citations

Double-stranded nucleic acids found in tissue infected with the satellite of tobacco ringspot virus

1977 • 21 citations

Low-molecular-weight RNAs associated with tobacco ringspot virus are satellites

1981 • 19 citations

Electron microscopy of double-stranded nucleic acids found in tissue infected with the satellite of tobacco ringspot virus

1982 • 19 citations

Synthesis of RNA complementary to potato spindle tuber viroid using Qβ replicase

1977 • 18 citations

Approaches to sequence analysis of¹²⁵I-labeled RNA

1979 • 17 citations

Potato Spindle Tuber Viroid-infected Tissues Contain RNA Complementary to the Entire Viroid

1982 • 15 citations

VIROIDS

1979 • 11 citations

Properties of RNA polymerases of healthy and citrus exocortis viroid-infected Gynura aurantiaca DC

1976 • 11 citations