Vascular Endothelial Growth Factor in Pulmonary Hypertension

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

1983 • 3,942 citations

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

1992 • 1,528 citations

Nucleotide sequence and expression of a novel human receptor-type tyrosine kinase gene (flt) closely related to the fms family.

1990 • 982 citations

Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors.

1992 • 900 citations

Exuberant endothelial cell growth and elements of inflammation are present in plexiform lesions of pulmonary hypertension.

1994 • 769 citations

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium.

1993 • 764 citations

Treatment of Primary Pulmonary Hypertension with Continuous Intravenous Prostacyclin (Epoprostenol)

1990 • 688 citations

Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. Modulation of gene expression by nitric oxide.

1995 • 590 citations

Endothelial receptor tyrosine kinases involved in angiogenesis.

1995 • 537 citations

Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues.

1992 • 443 citations

Induction of vascular endothelial growth factor expression by prostaglandin E2 and E1 in osteoblasts.

1994 • 393 citations

Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues

1993 • 369 citations

Suramin binds to platelet‐derived growth factor and inhibits its biological activity

1985 • 257 citations

Treatment of primary pulmonary hypertension intravenous epoprostenol (prostacyclin).

1987 • 167 citations

Hypoxia and platelet‐derived growth factor‐BB synergistically upregulate the expression of vascular endothelial growth factor in vascular smooth muscle cells

1995 • 165 citations

A Pathophysiological Study of 10 Cases of Hypoxic Cor Pulmonale

1988 • 154 citations

Suramin prevents neovascularisation and tumour growth through blocking of basic fibroblast growth factor activity

1992 • 118 citations

Pulmonary vascular remodelling in a high-altitude Aymara Indian

1991 • 17 citations

Prostacyclin and Iloprost — Thrombosis and Atherosclerosis

1987 • 2 citations