Site-Specific Cleavage of natural mRNA sequences by newly designed hairpin catalytic RNAs

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Simple RNA enzymes with new and highly specific endoribonuclease activities

1988 • 1,118 citations

A small catalytic oligoribonucleotide

1987 • 938 citations

Ribozymes as Potential Anti-HIV-1 Therapeutic Agents

1990 • 663 citations

Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites

1987 • 660 citations

Autolytic Processing of Dimeric Plant Virus Satellite RNA

1986 • 625 citations

Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroid

1986 • 583 citations

Imaging plate illuminates many fields

1988 • 495 citations

RNA catalytic properties of the minimum (-)sTRSV sequence

1989 • 360 citations

Self-cleavage of virusoid RNA is performed by the proposed 55-nucleotide active site

1987 • 323 citations

Substrate sequence effects on "hammerhead" RNA catalytic efficiency.

1990 • 238 citations

‘Hairpin’ catalytic RNA model: evidence for helices and sequence requirement for substrate RNA

1990 • 232 citations

Ribozyme mediated destruction of RNA in vivo.

1989 • 223 citations

Two sequences participating in the autolytic processing of satellite tobacco ringspot virus comple- mentary RNA

1989 • 176 citations

Specific gene suppression by engineered ribozymes in monkey cells.

1989 • 171 citations

Sequences required for self-catalysed cleavage of the satellite RNA of tobacco ringspot virus

1989 • 143 citations

Design of RNA enzymes distinguishing a single base mutation in RNA

1989 • 126 citations

Nucleotide sequence of the Escherichia coli prolipoprotein signal peptidase (lsp) gene.

1984 • 116 citations

Cleavage of specific sites of RNA by designed ribozymes

1988 • 113 citations

Construction of a series of several self‐cleaving RNA duplexes using synthetic 21‐mers

1988 • 112 citations

Ribozymes correctly cleave a model substrate and endogenous RNA in vivo.

1990 • 82 citations

[37] Compilation of self-cleaving sequences from plant virus satellite RNAs and other sources

1989 • 77 citations

Ribozymes that cleave an RNA sequence from human immunodeficiency virus: The effect of flanking sequence on rate

1991 • 66 citations

Nucleotide sequence predicts circularity and self-cleavage of 300-ribonucleotide satellite of arabis mosaic virus

1988 • 63 citations

Isolation and characterization of an Escherichia coli clone overproducing prolipoprotein signal peptidase.

1983 • 58 citations

Specific association between an endoribonucleolytic sequence from a satellite RNA and a substrate analogue containing a 2'-5' phosphodiester.

1990 • 41 citations

Cleavage of tRNA within the mature tRNA sequence by the catalytic RNA of RNase P: implication for the formation of the primer tRNA fragment for reverse transcription in copia retrovirus-like particles.

1990 • 36 citations

Ribozymes that cleave potato leafroll virus RNA within the coat protein and polymerase genes

1990 • 24 citations

Can ribozymes be used to regulate procaryote gene expression?

1989 • 20 citations

In vitro cleavage of HIV-1 vif RNA by a synthetic ribozyme

1991 • 15 citations