OB protein binds specifically to the choroid plexus of mice and rats.

Positional cloning of the mouse obese gene and its human homologue

1994 • 12,975 citations

Principles of neural science

1982 • 9,410 citations

Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene

1995 • 4,457 citations

Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice

1995 • 4,057 citations

Identification and expression cloning of a leptin receptor, OB-R

1995 • 3,498 citations

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

1995 • 3,302 citations

Evidence That the Diabetes Gene Encodes the Leptin Receptor: Identification of a Mutation in the Leptin Receptor Gene in db/db Mice

1996 • 2,185 citations

Changes in Energy Expenditure Resulting from Altered Body Weight

1995 • 1,926 citations

The role of neuropeptide Y in the antiobesity action of the obese gene product

1995 • 1,521 citations

Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis.

1979 • 1,145 citations

OBESE, A NEW MUTATION IN THE HOUSE MOUSE*

1950 • 1,020 citations

Insulin in the Brain: A Hormonal Regulator of Energy Balance*

1992 • 784 citations

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

1990 • 777 citations

Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map

1995 • 740 citations

Effects of parabiosis of obese with diabetes and normal mice

1973 • 728 citations

Recombinant ob protein reduces feeding and body weight in the ob/ob mouse.

1995 • 436 citations

Laboratory animals exhibiting obesity and diabetes syndromes

1977 • 417 citations

Familial Dependence of the Resting Metabolic Rate

1986 • 409 citations

Genetically transmitted obesity in rodents

1971 • 405 citations

The influence of genetic background on the expression of the obese (ob) gene in the mouse

1973 • 387 citations

Identification and cloning of ELF-1, a developmentally expressed ligand for the Mek4 and Sek receptor tyrosine kinases

1994 • 332 citations

The hypothalamic control of food intake in rats

1950 • 275 citations

Genetics of Obesity

1993 • 247 citations

Molecular mapping of the mouse ob mutation

1991 • 179 citations

Rat obesity gene fatty (fa) maps to chromosome 5: evidence for homology with the mouse gene diabetes (db).

1991 • 136 citations

Tackling a weighty problem

1992 • 123 citations

Recombinant OB-Gene Product Reduces Food-Intake in Fasted Mice

1995 • 117 citations

The Blood-brain barrier : cellular and molecular biology

1993 • 102 citations

Metabolic factors in the control of energy stores

1975 • 85 citations

Physiological Regulation of Body Weight and the Issue of Obesity

1989 • 50 citations

Evidence for separate receptors for insulin and insulin-like growth factor-I in choroid plexus of rat brain by quantitative autoradiography.

1990 • 24 citations

Inherited obesity-diabetes syndromes in the mouse.

1981 • 13 citations