Gap Junctional Communication Modulates Gene Expression in Osteoblastic Cells

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Calcium's Role in Mechanotransduction during Muscle Development

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In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria.

1983 • 1,661 citations

Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss.

1983 • 1,535 citations

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

1997 • 1,533 citations

Molecular Mechanisms Mediating Proliferation/Differentiation Interrelationships During Progressive Development of the Osteoblast Phenotype

1993 • 1,021 citations

Relationship of cell growth to the regulation of tissue‐specific gene expression during osteoblast differentiation

1990 • 934 citations

Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone.

1994 • 627 citations

Connexin family of gap junction proteins

1990 • 553 citations

The Bone Marrow-Derived Stromal Cell Lines MC3T3-G2/PA6 and ST2 Support Osteoclast-Like Cell Differentiation in Cocultures with Mouse Spleen Cells

1989 • 501 citations

Parathyroid Hormone-Responsive Clonal Cell Lines from Rat Osteosarcoma*

1980 • 483 citations

Morphological evidence of gap junctions between bone cells

1981 • 454 citations

Different pattern of alkaline phosphatase, osteopontin, and osteocalcin expression in developing rat bone visualized by in situ hybridization

1990 • 436 citations

Developmental expression of bone sialoprotein mRNA in rat mineralized connective tissues

1992 • 393 citations

Morphological and biochemical characterization of four clonal osteogenic sarcoma cell lines of rat origin.

1983 • 310 citations

Morphological study of intercellular junctions during osteocyte differentiation

1990 • 254 citations

ATP- and Gap Junction–dependent Intercellular Calcium Signaling in Osteoblastic Cells

1997 • 244 citations

Connexin43 and connexin45 form gap junctions with different molecular permeabilities in osteoblastic cells.

1994 • 240 citations

Cardiac myocytes express multiple gap junction proteins.

1992 • 234 citations

Connexin43 mediates direct intercellular communication in human osteoblastic cell networks.

1993 • 227 citations

Evidence that the gap junction protein connexin-43 is the ATP-induced pore of mouse macrophages

1991 • 195 citations

Characterization of an osteoblast-like clonal cell line which responds to both parathyroid hormone and calcitonin

1985 • 188 citations

Multiple connexins confer distinct regulatory and conductance properties of gap junctions in developing heart.

1992 • 175 citations

Transfected connexin45 alters gap junction permeability in cells expressing endogenous connexin43.

1995 • 174 citations

The role of cadherin in the generation of multinucleated osteoclasts from mononuclear precursors in murine marrow.

1995 • 171 citations

Opposing Effects of Fibroblast Growth Factor and Pertussis Toxin on Alkaline Phosphatase, Osteopontin, Osteocalcin, and Type I Collagen mRNA Levels in ROS 17/2.8 Cells

1989 • 169 citations

Glucocorticoid Regulation of Alkaline Phosphatase in the Osteoblastic Osteosarcoma Cell Line ROS 17/2.8*

1985 • 162 citations

Cyclic Stretch Enhances Gap Junctional Communication Between Osteoblastic Cells

1998 • 161 citations

Gap junctions. Multiplicity of controls in differentiated and undifferentiated cells and possible functional implications.

1993 • 158 citations

1,25-Dihydroxyvitamin D3 stimulates the synthesis of matrix gamma-carboxyglutamic acid protein by osteosarcoma cells. Mutually exclusive expression of vitamin K-dependent bone proteins by clonal osteoblastic cell lines.

1988 • 140 citations

Hormonal regulation of intercellular communication: parathyroid hormone increases connexin 43 gene expression and gap-junctional communication in osteoblastic cells.

1992 • 124 citations

Adequate connexin-mediated coupling is required for proper insulin production.

1995 • 121 citations

Osteoblasts are regulated by the cellular adhesion through ICAM-1 and VCAM-1

1995 • 118 citations

Gap Junctional Intercellular Communication Contributes to Hormonal Responsiveness in Osteoblastic Networks

1996 • 112 citations

Regulation of connexin43 expression and function by prostaglandin E ₂ (PGE ₂ ) and parathyroid hormone (PTH) in osteoblastic cells

1998 • 102 citations

Synergistic Induction of Osteocalcin Gene Expression

1996 • 100 citations

Activity of the rat osteocalcin basal promoter in osteoblastic cells is dependent upon homeodomain and CP1 binding motifs.

1994 • 98 citations

Regulation of connexin43 expression and function by prostaglandin E2 (PGE2) and parathyroid hormone (PTH) in osteoblastic cells

1998 • 95 citations

Dominant-negative abrogation of connexin-mediated cell growth control by mutant connexin genes

1997 • 78 citations

Stimulation of human osteoblast differentiation and function by ipriflavone and its metabolites

1994 • 75 citations

Gap junction-mediated cell-to-cell communication in bovine and human adrenal cells. A process whereby cells increase their responsiveness to physiological corticotropin concentrations.

1995 • 74 citations

Interaction of human parathyroid hormone-related peptide with parathyroid hormone receptors in clonal rat osteosarcoma cells.

1988 • 63 citations

Gap junctions modulate tissue contractility and alpha 1 adrenergic agonist efficacy in isolated rat aorta.

1993 • 61 citations

Gap junction proteins exhibit early and specific expression during intramembranous bone formation in the developing chick mandible

1994 • 57 citations

Parathyroid hormone depresses cytosolic pH and DNA synthesis in osteoblast-like cells

1988 • 56 citations

Isolation and characterization of gap junctions in the osteoblastic MC3T3-E1 cell line

1994 • 55 citations

Restoration of Cell-to-Cell Communication in Thyroid Cell Lines by Transfection with and Stable Expression of the Connexin-32 Gene

1997 • 42 citations

Cell-cell interactions in the osteogenic compartment of bone

1988 • 26 citations

Bone Gla Protein Messenger Ribonucleic Acid is Regulated by Both 1,25-Dihydroxyvitamin D₃and 3′,5′-Cyclic Adenosine Monophosphate in Rat Osteosarcoma Cells

1989 • 25 citations

Expression of the osteonectin gene potentially controlled by multiple Cis- and trans-acting factors in cultured bone cells

1991 • 18 citations

Osteoblast density and the evolution of BMUs in vertebral osteoporosis

1993 • 7 citations