Low-dose inhaled nitric oxide improves the oxygenation and ventilation of infants and children with acute, hypoxemic respiratory failure

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

Inhaled Nitric Oxide for the Adult Respiratory Distress Syndrome

1993 • 1,811 citations

The biology of nitrogen oxides in the airways.

1994 • 928 citations

Effects of inhaled nitric oxide in patients with acute respiratory distress syndrome

1998 • 754 citations

Time‐course and dose‐response of nitric oxide inhalation for systemic oxygenation and pulmonary hypertension in patients with adult respiratory distress syndrome

1993 • 396 citations

Bronchodilator action of inhaled nitric oxide in guinea pigs.

1992 • 326 citations

Inhalation of Nitric Oxide Modulates Adult Human Bronchial Tone

1993 • 296 citations

Prolonged Inhalation of Low Concentrations of Nitric Oxide in Patients with Severe Adult Respiratory Distress Syndrome

1994 • 282 citations

Inhaled nitric oxide in infants referred for extracorporeal membrane oxygenation: Dose response

1994 • 267 citations

Acute effects of inhaled nitric oxide in children with severe hypoxemic respiratory failure

1994 • 223 citations

Inhaled nitric oxide in acute respiratory failure: Dose-response curves

1994 • 190 citations

Prostaglandin E1 and Nitroglycerin Reduce Pulmonary Capillary Pressure but Worsen Ventilation—Perfusion Distributions in Patients with Adult Respiratory Distress Syndrome

1989 • 173 citations

Adult respiratory distress syndrome in children: Associated disease, clinical course, and predictors of death

1993 • 168 citations

Factors influencing cardiopulmonary effects of inhaled nitric oxide in acute respiratory failure.

1995 • 156 citations

Mortality rates and prognostic variables in children with adult respiratory distress syndrome

1991 • 138 citations

Acute hypoxemic respiratory failure in infants and children

1992 • 106 citations

Adult Respiratory Distress Syndrome in a Pediatric Intensive Care Unit: Predisposing Conditions, Clinical Course, and Outcome

1981 • 103 citations

Acute Response to Inhaled Nitric Oxide in Newborns With Respiratory Failure and Pulmonary Hypertension

1996 • 99 citations

Predicting Death in Pediatric Patients With Acute Respiratory Failure

1995 • 92 citations

Pathophysiology of congenital diaphragmatic hernia VIII: Inhaled nitric oxide requires exogenous surfactant therapy in the lamb model of congenital diaphragmatic hernia

1995 • 82 citations

Predictors of Mortality in Children with Respiratory Failure: Possible Indications for ECMO

1990 • 81 citations

Inhaled nitric oxide in neonatal and pediatric acute respiratory distress syndrome

1996 • 78 citations

Inhaled nitric oxide reduces the utilization of extracorporeal membrane oxygenation in persistent pulmonary hypertension of the newborn

1997 • 72 citations

Alveolar-arterial oxygen gradient as a predictor of outcome in patients with nonneonatal pediatric respiratory failure

1991 • 69 citations

Inhaled nitric oxide in children with severe lung disease

1996 • 66 citations

Reversal of bronchoconstriction by inhaled nitric oxide. Histamine versus methacholine.

1994 • 49 citations

Improvement in VA/Q distributions during inhalation of nitric oxide in pigs with methacholine-induced bronchoconstriction.

1995 • 47 citations

Response to nitric oxide inhalation in early acute lung injury

1996 • 42 citations

Cardiopulmonary abnormalities in severe acute respiratory failure

1984 • 38 citations

Effect of nitric oxide in meconium aspiration syndrome after treatment with surfactant

1997 • 33 citations

The effect of inhaled nitric oxide in pediatric asthma.

1996 • 30 citations

Further studies on the kinetics and equilibria of the reactions of nitric oxide with haemoproteins

1965 • 29 citations