How cells know they are in G1 or G2

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

Mammalian G1 cyclins

1993 • 1,990 citations

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts.

1993 • 1,057 citations

Cyclin-Dependent Regulation of G ₁ in Mammalian Fibroblasts

1993 • 767 citations

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation

1994 • 543 citations

CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.

1993 • 521 citations

Morphogenesis in the yeast cell cycle: regulation by Cdc28 and cyclins.

1993 • 509 citations

Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins.

1993 • 492 citations

Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle

1994 • 478 citations

Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated cdc2 kinase

1993 • 456 citations

The fission yeast cdc18+ gene product couples S phase to START and mitosis

1993 • 446 citations

The roles of Drosophila cyclins A and B in mitotic control

1990 • 429 citations

Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2

1990 • 401 citations

Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex

1994 • 393 citations

Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins

1993 • 376 citations

Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene

1994 • 356 citations

Involvement of p34cdc2 in establishing the dependency of S phase on mitosis

1991 • 340 citations

Cell Cycle Regulation in the Yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe

1991 • 326 citations

FAR1 links the signal transduction pathway to the cell cycle machinery in yeast

1993 • 290 citations

Cell cycle regulted transcription in yeast

1994 • 283 citations

On the synthesis and destruction of A- and B-type cyclins during oogenesis and meiotic maturation in Xenopus laevis.

1991 • 262 citations

The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo.

1992 • 236 citations

cdt1 is an essential target of the Cdc10/Sct1 transcription factor: requirement for DNA replication and inhibition of mitosis.

1994 • 232 citations

Fission yeast cut5+, required for S phase onset and M phase restraint, is identical to the radiation-damage repair gene rad4+

1993 • 231 citations

Suppression of DNA replication via Mos function during meiotic divisions in Xenopus oocytes.

1994 • 227 citations

Reversible arrest of proliferation of rat 3Y1 fibroblasts in both the G1 and G2 phases by trichostatin A

1988 • 192 citations

Cell cycle progression in the developing Drosophila eye: roughex encodes a novel protein required for the establishment of G1

1994 • 191 citations

Negative regulation of FAR1 at the Start of the yeast cell cycle.

1993 • 148 citations

Effects of leptomycin B on the cell cycle of fibroblasts and fission yeast cells

1990 • 123 citations

Uncoupled cell cycle without mitosis induced by a protein kinase inhibitor, K-252a.

1991 • 121 citations

Genetic analysis of Cln/Cdc28 regulation of cell morphogenesis in budding yeast.

1993 • 106 citations

The cyclin B2 component of MPF is a substrate for the c-mosxe proto-oncogene product

1990 • 105 citations

Identification of a Gl-type cyclin puc1+ in the fission yeast Schizosaccharomyces pombe

1991 • 94 citations

A B-type cyclin negatively regulates conjugation via interacting with cell cycle ‘start’ genes in fission yeast.

1994 • 92 citations

The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1

1992 • 90 citations

A single p34cdc2 protein kinase (encoded by nimXcdc2) is required at G1 and G2 in Aspergillus nidulans

1994 • 85 citations

Interaction between the Cig1 and Cig2 B-type cyclins in the fission yeast cell cycle.

1994 • 80 citations

The c-mos gene product is required for cyclin B accumulation during meiosis of mouse eggs.

1991 • 78 citations

Correction: Identification of a Gl-type cyclin puc+ in the fission yeast Schizosaccharomyces pombe

1991 • 63 citations

Two fission yeast B-type cyclins, cig2 and Cdc13, have different functions in mitosis.

1993 • 62 citations

roughex is a dose-dependent regulator of the second meiotic division during Drosophila spermatogenesis

1994 • 55 citations

Analysis of the Schizosaccharomyces pombe cyclin puc1: evidence for a role in cell cycle exit

1994 • 48 citations