Cytoskeletal Rearrangements and Transcriptional Activation of c-fos Serum Response Element by Rho-kinase

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Antibodies, a laboratory manual

1989 • 12,929 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 • 3,628 citations

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

1996 • 2,843 citations

Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)

1996 • 1,964 citations

Physiology of the Gastrointestinal Tract.

1987 • 1,948 citations

pEF-BOS, a powerful mammalian expression vector

1990 • 1,641 citations

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

1996 • 1,614 citations

The Rho family GTPases RhoA, Racl , and CDC42Hsregulate transcriptional activation by SRF

1995 • 1,280 citations

Formation of Actin Stress Fibers and Focal Adhesions Enhanced by Rho-Kinase

1997 • 1,085 citations

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.

1996 • 1,045 citations

High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment

1984 • 898 citations

The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

1996 • 872 citations

The p160 RhoA-Binding Kinase ROKα Is a Member of a Kinase Family and Is Involved in the Reorganization of the Cytoskeleton

1996 • 866 citations

Microinjection of recombinant p21rho induces rapid changes in cell morphology.

1990 • 720 citations

A Novel Serine/Threonine Kinase Binding the Ras-related RhoA GTPase Which Translocates the Kinase to Peripheral Membranes

1995 • 711 citations

Baculovirus Expression Vectors: the Requirements for High Level Expression of Proteins, Including Glycoproteins

1987 • 677 citations

The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

1994 • 647 citations

Adhesion in cell migration

1995 • 520 citations

Signal transduction pathways regulating Rho-mediated stress fibre formation: requirement for a tyrosine kinase.

1994 • 469 citations

Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction.

1992 • 458 citations

Identification of a Putative Target for Rho as the Serine-Threonine Kinase Protein Kinase N

1996 • 417 citations

Protein Kinase N (PKN) and PKN-Related Protein Rhophilin as Targets of Small GTPase Rho

1996 • 384 citations

Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).

1993 • 363 citations

Regulation of Smooth Muscle Contractile Elements by Second Messengers

1989 • 357 citations

CONTROL OF NONMUSCLE MYOSINS BY PHOSPHORYLATION

1992 • 338 citations

Role of guanine nucleotide-binding proteins--ras-family or trimeric proteins or both--in Ca2+ sensitization of smooth muscle.

1996 • 280 citations

Regulation and function of the Rho subfamily of small GTPases

1994 • 233 citations

A rho-like protein is involved in the organisation of the contractile ring in dividing sand dollar eggs

1993 • 230 citations

Inhibition of PMA-induced, LFA-1-dependent lymphocyte aggregation by ADP ribosylation of the small molecular weight GTP binding protein, rho.

1993 • 223 citations

ADP-ribosylation of rho p21 inhibits lysophosphatidic acid-induced protein tyrosine phosphorylation and phosphatidylinositol 3-kinase activation in cultured Swiss 3T3 cells.

1993 • 212 citations

Activation of platelet phosphatidylinositide 3-kinase requires the small GTP-binding protein Rho.

1993 • 211 citations

Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility.

1994 • 199 citations

A novel partner for the GTP‐bound forms of rho and rac

1995 • 166 citations

Isolation of a NCK-associated Kinase, PRK2, an SH3-binding Protein and Potential Effector of Rho Protein Signaling

1996 • 141 citations

Phosphorylation of Glial Fibrillary Acidic Protein at the Same Sites by Cleavage Furrow Kinase and Rho-associated Kinase

1997 • 131 citations

13 Regulation of Contractile Activity

1987 • 118 citations

Involvement of the GTP binding protein Rho in constitutive endocytosis in Xenopus laevis oocytes.

1995 • 110 citations

Sequestration of a G-protein βγ Subunit or ADP-ribosylation of Rho Can Inhibit Thrombin-induced Activation of Platelet Phosphoinositide 3-Kinases

1995 • 93 citations

Identification of multiple, novel, protein kinase C‐related gene products

1994 • 45 citations

[43] Mammalian cell microinjection assay

1995 • 14 citations

Quantitation of cytoskeletal fibers in fluorescence images: Stress fiber disassembly accompanies dephosphorylation of the regulatory light chains of myosin II

1993 • 9 citations