Enhanced neurotrophic activity in Alzheimer's disease cortex is not associated with down-regulation of metallothionein-III (GIF)

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

1991 • 4,669 citations

The molecular pathology of Alzheimer's disease

1991 • 2,603 citations

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

1990 • 1,975 citations

A Method for Isolation of Intact, Translationally Active Ribonucleic Acid

1983 • 1,469 citations

Determination of sulfhydryl groups with 2,2′- or 4,4′-dithiodipyridine

1967 • 978 citations

Metallothionein: a Cadmium- and Zinc-containing Protein from Equine Renal Cortex

1960 • 965 citations

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

1991 • 887 citations

A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and alzheimer disease

1981 • 698 citations

The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein

1991 • 689 citations

Metallothionein: a Cadmium and Zinc-containing Protein from Equine Renal Cortex

1961 • 685 citations

MT-III, a brain-specific member of the metallothionein gene family.

1992 • 558 citations

Chemistry and Biochemistry of Metallothionein

1987 • 536 citations

Cell lineage ablation in transgenic mice by cell-specific expression of a toxin gene

1987 • 479 citations

Amyloid β Protein Enhances the Survival of Hippocampal Neurons in Vitro

1989 • 470 citations

A practical approach for quantitating specific mRNAs by solution hybridization

1983 • 427 citations

Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: Lesion effects in the rat brain and levels in Alzheimer's disease

1986 • 335 citations

Massive somatodendritic sprouting of cortical neurons in Alzheimer's disease

1988 • 308 citations

Binding of cadmium ions by rat liver and kidney

1972 • 261 citations

Metallothionein III : biological roles and medical implications

1993 • 253 citations

Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease

1993 • 234 citations

Increased S100β neurotrophic activity in Alzheimer's disease temporal lobe

1992 • 214 citations

Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease.

1992 • 191 citations

Basic fibroblast growth factor in Alzheimer's disease

1990 • 173 citations

Microtubular reorganization and dendritic growth response in alzheimer's disease

1989 • 159 citations

Order of metal binding in metallothionein.

1983 • 152 citations

Neuropil Threads Occur in Dendrites of Tangle—Bearing Nerve Cells

1988 • 147 citations

Neurotrophic action of Alzheimer's disease brain extract is due to the loss of inhibitory factors for survival and neurite formation of cerebral cortical neurons

1989 • 112 citations

Alzheimer's disease brain extract stimulates the survival of cerebral cortical neurons from neonatal rats

1988 • 111 citations

Isolation and purification of cadmium binding proteins from rat liver

1974 • 101 citations

Molecular cloning of rat growth inhibitory factor cDNA and the expression in the central nervous system

1993 • 94 citations

Neurotrophic agents may exacerbate the pathologic cascade of Alzheimer's disease

1989 • 89 citations

Neuronal alterations in patients with dementia: a Golgi study on biopsy samples

1990 • 83 citations

Normal β-NGF content in Alzheimer's disease cerebral cortex and hippocampus

1991 • 82 citations

Effects of various trace metals on the binding of cadmium to rat hepatic metallothionein determined by the Cd/hemoglobin affinity assay

1985 • 32 citations

Tangle-bearing neurons show more extensive dendritic trees than tangle-free neurons in area CA1 of the hippocampus in Alzheimer's disease

1991 • 21 citations

Towards an improved survival of rat brain neurons in culture by cerebrospinal fluid of patients with senile dementia of Alzheimer's type

1993 • 9 citations