Novel amidine-containing peptidyl phosphonates as irreversible inhibitors for blood coagulation and related serine proteases

A new and rapid colorimetric determination of acetylcholinesterase activity

1961 • 25,114 citations

On the size of the active site in proteases. I. Papain

1967 • 5,150 citations

The preparation and properties of two new chromogenic substrates of trypsin

1961 • 3,319 citations

Determination of sulfhydryl groups with 2,2′- or 4,4′-dithiodipyridine

1967 • 978 citations

INHIBITION OF THROMBIN AND TRYPSIN BY TRIPEPTIDE ALDEHYDES

1978 • 140 citations

Mammalian tissue trypsin-like enzymes. Comparative reactivities of human skin tryptase, human lung tryptase, and bovine trypsin with peptide 4-nitroanilide and thioester substrates.

1983 • 102 citations

Mapping the active sites of bovine thrombin, factor IXa, factor Xa, factor XIa, factor XIIa, plasma kallikrein, and trypsin with amino acid and peptide thioesters: development of new sensitive substrates

1981 • 93 citations

Inhibition of chymotrypsin by phosphonate and phosphonamidate peptide analogs

1986 • 79 citations

Highly selective tripeptide thrombin inhibitors

1993 • 68 citations

Substrate-related phosphonopeptides, a new class of thrombin inhibitors

1991 • 65 citations

Synthesis of phosphonopeptides as thrombin inhibitors

1992 • 50 citations

A convenient synthesis of N-protected diphenyl phosphonate ester analogues of ornithine, lysine and homolysine.

1993 • 43 citations