Autoimmunity in non-human primates: the role of major histocompatibility complex and T cells, and implications for therapy

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

Autoimmunity to type II collagen an experimental model of arthritis.

1977 • 1,599 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

1981 • 917 citations

HLA and Disease Associations

1985 • 893 citations

Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis

1989 • 588 citations

Nomenclature for the major histocompatibility complexes of different species: a proposal

1990 • 546 citations

The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens

1988 • 491 citations

Arthritis induced by a T-lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycans.

1985 • 463 citations

Arthritis in rats after systemic injection of streptococcal cells or cell walls.

1977 • 437 citations

Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy

1989 • 394 citations

Humoral and Cellular Sensitivity to Collagen in Type II Collagen-Induced Arthritis in Rats

1978 • 259 citations

T cell recognition as the target for immune intervention in autoimmune disease

1989 • 218 citations

How some T cells escape tolerance induction

1989 • 216 citations

T Cell Receptor Peptide Therapy Triggers Autoregulation of Experimental Encephalomyelitis

1991 • 202 citations

Isoallergic Encephalomyelitis and Radiculitis in Guinea Pigs After One Injection of Brain and Mycobacteria in Water-in-Oil Emulsion

1947 • 199 citations

Involvement of distinct murine T-cell receptors in the autoimmune encephalitogenic response to nested epitopes of myelin basic protein.

1988 • 172 citations

Control of the Immune Response at the Level of Antigen-Presenting Cells: A Comparison of the Function of Dendritic Cells and B Lymphocytes

1989 • 163 citations

Prevention of experimental encephalomyelitis with peptides that block interaction of T cells with major histocompatibility complex proteins.

1989 • 135 citations

Experimental models in rheumatoid disease

1964 • 111 citations

Collagen induced arthritis as an experimental model for rheumatoid arthritis

1989 • 108 citations

Protection from experimental allergic encephalomyelitis conferred by a monoclonal antibody directed against a shared idiotype on rat T cell receptors specific for myelin basic protein.

1988 • 104 citations

Autoimmunity to collagen in adjuvant arthritis of rats.

1980 • 102 citations

Immunogenetics of type II collagen autoimmunity and susceptibility to collagen arthritis.

1988 • 100 citations

HLA AND DISEASE ASSOCIATIONS

1984 • 96 citations

Multiple discrete encephalitogenic epitopes of the autoantigen myelin basic protein include a determinant for I-E class II-restricted T cells.

1988 • 92 citations

Genetic control of the development of experimental allergic encephalomyelitis in rats. Separation of MHC and non-MHC gene effects.

1988 • 70 citations

Regulatory circuits in autoimmunity: recruitment of counter‐regulatory CD8⁺ T cells by encephalitogenic CD4⁺ T line cells

1988 • 64 citations

Experimental immune mediated arthritis in rhesus monkeys

1990 • 49 citations

Collagen‐induced arthritis in an outbred group of rhesus monkeys comprising responder and nonresponder animals. Relationship between the course of arthritis and collagen‐specific immunity

1991 • 48 citations

Successful treatment of EAE in rhesus monkeys with MHC class II specific monoclonal antibodies

1988 • 38 citations

Experimental allergic encephalomyelitis in rhesus monkeys: II. Treatment of EAE with anti-T lymphocyte subset monoclonal antibodies.

1987 • 31 citations

RFLP analysis of theHLA-, ChLA-, andRhLA-DQ alpha chain gene regions: Conservation of restriction sites during evolution

1989 • 28 citations

Experimental allergic encephalomyelitis in rhesus monkeys: I. Immunological parameters in EAE resistant and susceptible rhesus monkeys.

1987 • 26 citations

THE MAJOR HISTOCOMPATIBILITY COMPLEX OF RHESUS MONKEYS: XIII. CURRENT KNOWLEDGE OF DR AND OTHER B‐CELL SPECIFIC ANTIGENS †

1980 • 19 citations

RFLP analysis of the rhesus monkey MHC class II DR subregion

1991 • 17 citations

Polymorphism and complexity of HLA-DR: evidence for intra-HLA-DR region crossing-over events

1988 • 15 citations

The major histocompatibility complex of Rhesus monkeys.: XIV. A family study of DR and other RhLA‐linked cell membrane antigens*

1981 • 12 citations

The Phylogeny of T Cell Antigens

1986 • 11 citations

The major histocompatibility complex: a key to a better understanding of evolution.

1980 • 3 citations