Biology of endothelin receptors in the collecting duct

Endothelin: 20 years from discovery to therapyThis article is one of a selection of papers published in the special issue (part 2 of 2) on Forefronts in Endothelin.

2008 • 297 citations

Salt-sensitive hypertension in endothelin-B receptor–deficient rats

2000 • 290 citations

Endothelin, a peptide inhibitor of Na(+)-K(+)-ATPase in intact renaltubular epithelial cells

1989 • 285 citations

Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention.

2004 • 249 citations

Avosentan Reduces Albumin Excretion in Diabetics with Macroalbuminuria

2009 • 235 citations

Different localization of two types of endothelin receptor mRNA in microdissected rat nephron segments using reverse transcription and polymerase chain reaction assay.

1992 • 211 citations

Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention

2006 • 208 citations

Collecting duct–specific knockout of endothelin-1 causes hypertension and sodium retention

2004 • 208 citations

Ligand-dependent Differences in the Internalization of Endothelin A and Endothelin B Receptor Heterodimers

2004 • 130 citations

Effects of endothelin on peptide-dependent cyclic adenosine monophosphate accumulation along the nephron segments of the rat.

1990 • 127 citations

Endothelin-1 inhibits AVP-stimulated osmotic water permeability in rat inner medullary collecting duct

1991 • 120 citations

Profile of past and current clinical trials involving endothelin receptor antagonists: the novel "-sentan" class of drug.

2006 • 113 citations

Collecting duct-specific knockout of endothelin-1 alters vasopressin regulation of urine osmolality

2005 • 103 citations

Regulation of the epithelial Na⁺channel by endothelin-1 in rat collecting duct

2008 • 100 citations

Combined knockout of collecting duct endothelin A and B receptors causes hypertension and sodium retention

2008 • 99 citations

Collecting duct-specific knockout of the endothelin A receptor alters renal vasopressin responsiveness, but not sodium excretion or blood pressure

2005 • 97 citations

Localization of endothelin peptides in human kidney

1996 • 91 citations

Endothelin B receptor mediates ET-1 effects on cAMP and PGE2 accumulation in rat IMCD

1993 • 89 citations

Collecting Duct-Derived Endothelin Regulates Arterial Pressure and Na Excretion via Nitric Oxide

2008 • 86 citations

Mechanism of the Nitric Oxide-Induced Blockade of Collecting Duct Water Permeability

1996 • 86 citations

Contribution of Endothelin A Receptors in Endothelin 1–Dependent Natriuresis in Female Rats

2008 • 83 citations

Functional Role of ET _B Receptors in the Renal Medulla

2003 • 83 citations

Distribution of Endothelin Receptor Subtypes ET_A and ET_B in the Rat Kidney

2006 • 82 citations

Effects of ET-1 on water and chloride transport in cortical collecting ducts of the rat

1993 • 79 citations

Regulation of amiloride-sensitive Na+ channels by endothelin-1 in distal nephron cells

1996 • 78 citations

Renal medullary ET_Breceptors produce diuresis and natriuresis via NOS1

2008 • 77 citations

Characterization of endothelin receptors in the inner medullary collecting duct of the rat.

1992 • 75 citations

Two distinct human endothelin B receptors generated by alternative splicing from a single gene.

1994 • 67 citations

Endothelin-1 stimulates NO production and inhibits cAMP accumulation in rat inner medullary collecting duct through independent pathways

2005 • 61 citations

Comparison of Endothelin-A and Endothelin-B Receptor Distribution Visualized by Radioligand Binding versus Immunocytochemical Localization using Subtype Selective Antisera

2004 • 50 citations

Fluorescence Resonance Energy Transfer Analysis Reveals the Existence of Endothelin-A and Endothelin-B Receptor Homodimers

2004 • 49 citations

Endothelin-1 and endothelin-3 binding to rat nephrons

1993 • 48 citations

Altered AT ₁ Receptor Regulation of ETB Receptors in Renal Proximal Tubule Cells of Spontaneously Hypertensive Rats

2005 • 39 citations

Renal D3 dopamine receptor stimulation induces natriuresis by endothelin B receptor interactions

2008 • 35 citations

Calcium regulation of endothelin-1 synthesis in rat inner medullary collecting duct

2007 • 34 citations

Endothelin_A (ET_A) and ET_B receptor‐mediated regulation of nitric oxide synthase 1 (NOS1) and NOS3 isoforms in the renal inner medulla

2007 • 25 citations

Regulation of kidney acid excretion by endothelins

2006 • 24 citations

Endothelin and nitric oxide mediate adaptation of the cortical collecting duct to metabolic acidosis

2006 • 23 citations

Role of prostaglandins in collecting duct-derived endothelin-1 regulation of blood pressure and water excretion

2007 • 23 citations

Differential Regulation of ETA and ETB in the Renal Tissue of Rats with Compensated and Decompensated Heart Failure

2004 • 22 citations

Cloning and Functional Identification of Novel Endothelin Receptor Type A Isoforms in Pituitary

2007 • 22 citations

Specific endothelin binding sites in renal medullary collecting duct cells: lack of interaction with ANP binding and cGMP signalling

1992 • 19 citations

Endothelin A receptor-like immunoreactivity on the basal infoldings of rat renal tubules and collecting ducts

2008 • 19 citations

Endothelin ETB receptor heterodimerization: beyond the ETA receptor

2008 • 18 citations

Endothelin B receptor antagonism in the rat renal medulla reduces urine flow rate and sodium excretion.

2006 • 17 citations

Endothelin-1 and endothelin receptor status in kidney transplants undergoing acute rejection

1999 • 12 citations

Endothelin-1, endothelin-3 and their receptors (endothelin_Aand endothelin_B) in chronic renal transplant rejection in rats

2000 • 12 citations

Desensitization of endothelin-1 binding by vasopressin via a cAMP-mediated pathway in rat CCD

1995 • 12 citations

[Immunohistochemical study on endothelin in rat kidney].

1997 • 12 citations

Endothelin-1, endothelin-3 and their receptors (endothelin A and endothelin B ) in chronic renal transplant rejection in rats 1

2000 • 7 citations

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