Obesity: A Serious Symptom

The role of depot fat in the hypothalamic control of food intake in the rat

1953 • 1,400 citations

Plasma Insulin Responses to Oral and Intravenous Glucose: Studies in Normal and Diabetic Subjects*

1967 • 908 citations

Plasma Amino Acid Levels and Insulin Secretion in Obesity

1969 • 772 citations

Stimulation of insulin secretion by amino acids.

1966 • 707 citations

The Significance of Basal Insulin Levels in the Evaluation of the Insulin Response to Glucose in Diabetic and Nondiabetic Subjects*

1967 • 664 citations

The role of adipose cell size and adipose tissue insulin sensitivity in the carbohydrate intolerance of human obesity

1968 • 587 citations

Excessive Insulin Response to Glucose in Obese Subjects as Measured by Immunochemical Assay

1963 • 573 citations

Obesity and Eating

1968 • 545 citations

Surgical treatment of obesity

1969 • 542 citations

FOREARM METABOLISM IN OBESITY AND ITS RESPONSE TO INTRA-ARTERIAL INSULIN. CHARACTERIZATION OF INSULIN RESISTANCE AND EVIDENCE FOR ADAPTIVE HYPERINSULINISM*

1962 • 499 citations

Genetically transmitted obesity in rodents

1971 • 405 citations

Dietary Obesity in Rats: Body Weight and Body Fat Accretion in Seven Strains of Rats

1970 • 349 citations

Cellularity of obese and nonobese human adipose tissue.

1970 • 339 citations

Plasma Insulin Responses to Glucose and Tolbutamide of Normal Weight and Obese Diabetic and Nondiabetic Subjects

1966 • 338 citations

Regulation of Food Intake and Obesity

1967 • 317 citations

Effect on Hepatic Morphology of Treatment of Obesity by Fasting, Reducing Diets and Small-Bowel Bypass

1970 • 297 citations

Obesity, Social Class, and Mental Illness

1962 • 263 citations

Number and size of adipose tissue fat cells in relation to metabolism in human obesity

1971 • 244 citations

Nervous Regulation of Food Intake

1961 • 237 citations

Improved Glucose Tolerance with High Carbohydrate Feeding in Mild Diabetes

1971 • 232 citations

Experimental obesity in man.

1968 • 227 citations

Hyperalimentation in Normal Animals Produced by Protamine Insulin

1940 • 202 citations

Reciprocal Hunger-Regulating Circuits Involving Alpha-and Beta-Adrenergic Receptors Located, Respectively, in the Ventromedial and Lateral Hypothalamus

1970 • 187 citations

STUDIES OF INSULIN AND GROWTH HORMONE SECRETION IN HUMAN OBESITY.

1964 • 179 citations

Insulin Secretion in Obesity

1967 • 165 citations

Effect of Diet Composition on the Hyperinsulinemia of Obesity

1971 • 155 citations

Polyarthritis in Obese Patients with Intestinal Bypass

1971 • 142 citations

Dependence of Hypothalamic Obesity on Insulin, the Pituitary and the Adrenal Gland11

1972 • 139 citations

Some Endocrine and Metabolic Aspects of Obesity

1970 • 132 citations

Action of glucocorticoid as inducer and insulin as suppressor of biosynthesis of hepatic gluconeogenic enzymes

1965 • 126 citations

Measurements of insulin activities in pancreas and serum of mice with spontaneous (?obese? and ?New Zealand obese?) and induced (goldthioglucose) obesity and hyperglycemia, with considerations on the pathogenesis of the spontaneous syndrome

1967 • 125 citations

Insulin Resistance in Genetically Obese, Hyperglycemic Mice

1971 • 115 citations

Feeding: Neural Control of Intake

1971 • 113 citations

Plasma Glucose, Free Fatty Acids, and Immunoreactive Insulin in Sixty-six Obese Children: Studies in Reference to a Family History of Diabetes Mellitus

1968 • 109 citations

The results of small intestine bypass operations for the treatment of obesity.

1971 • 109 citations

Effect of arginine on serum levels of insulin and growth hormone in obese subjects

1967 • 107 citations

Lipogenesis in Human Adipose Tissue: Some Effects of Nibbling and Gorging

1972 • 98 citations

Alcohol Hypoglycemia

1966 • 97 citations

Effect of Meal Frequency in Schoolchildren

1966 • 93 citations

Occurrence of Acute Wernicke's Encephalopathy during Prolonged Starvation for the Treatment of Obesity

1966 • 93 citations

Cortisol Metabolism in Obesity

1964 • 87 citations

DEATH DURING THERAPEUTIC STARVATION FOR OBESITY

1968 • 81 citations

Metabolic Effects of Weight Loss in Obese Subjects: Changes in Plasma Substrate Levels, Insulin and Growth Hormone Responses

1971 • 79 citations

Salt Excretion of Fasting Patients

1960 • 76 citations

Cortisol Production Rates in Obesity

1962 • 73 citations

Effects of hyothalamic lesions at different loci on development of hyperinsulinemia and obesity in the weanling rat

1971 • 72 citations

Food and temperature.

1960 • 69 citations

The Myth of Diet in the Management of Obesity

1970 • 64 citations

Measurement of Subcutaneous Fat Cells from Obese Patients

1970 • 61 citations

Lactic Acidosis and Death after the Treatment of Obesity by Fasting

1965 • 59 citations

Peripheral metabolism of glucose and free fatty acids during oral glucose tolerance tests

1965 • 58 citations

Studies on Adipose Tissue from Obese Patients with or without Diabetes Mellitus

1966 • 58 citations

Use of independent measurement of body fat to evaluate overweight and underweight

1971 • 57 citations

CHARACTERISTICS OF THE INCREASED ADRENOCORTICAL FUNCTION OBSERVED IN MANY OBESE PATIENTS*

1965 • 54 citations

Insulin resistance in hyperglyceridemia

1965 • 53 citations

Amelioration of insulin resistance in obese mice

1971 • 52 citations

EFFECT OF DIET, SULPHONYLUREAS, AND PHENFORMIN ON PERIPHERAL GLUCOSE UPTAKE IN DIABETES AND OBESITY

1968 • 50 citations

Relationship between Obesity, Chemical Diabetes and Beta Pancreatic Function in Children

1969 • 49 citations

Frequency of Feeding, Weight Reduction, and Body Composition1

1971 • 49 citations

Relationships between oxygen consumption and body composition of obese patients

1970 • 46 citations

Glucose tolerance and time sequence of adiposity, hyperinsulinemia and hyperglycemia in obese-hyperglycemic mice (obob)

1970 • 45 citations

Insulin Response to Glucagon: The Opposing Effects of Diabetes and Obesity

1969 • 43 citations

Weight Loss during Fasting: Implications for the Obese

1970 • 42 citations

Implications of growth hormone release in sleep

1970 • 42 citations

Effect of Weight Loss on the Growth Hormone Response to Arginine Infusion in Obesity

1971 • 40 citations

OBESITY AS AN ADDITIONAL FACTOR IN THE PATHOGENESIS OF DIABETES

1968 • 37 citations

Pituitary Response to Insulin-Induced Hypoglycemia in Obese Subjects Before and After Fasting

1970 • 36 citations

Metabolic Differences between Obese Overweight and Muscular Overweight Men

1971 • 35 citations

Exaggerated Insulin Response to Glucagon in Simple Obesity

1967 • 35 citations

Regulation of Adipose Mass: Control of Fat Cell Development and Lipid Content

1970 • 35 citations

Effect of weight reduction, triiodothyronine, and diethylstilbestrol on growth hormone in obesity

1969 • 34 citations

Magnesium Depletion During Prolonged Fasting of Obese Males

1969 • 33 citations

Porphyria Precipitated by Fasting

1967 • 33 citations

CHEMICAL ANALYSIS OF THE BODY

1965 • 29 citations

Glucocorticoid-Induced Obesity—a Model and a Challenge

1968 • 29 citations

A CONTROLLED STUDY OF THYROID ANALOGS IN THE THERAPY OF OBESITY

1967 • 28 citations

Effect of Protein Meals on Plasma Insulin in Mildly Diabetic Patients

1969 • 27 citations

Insulin release in response to oral glucose in obesity: The effect of reduction of body weight

1969 • 27 citations

Effect of Obesity on Insulin Sensitivity of Human Adipose Tissue

1972 • 26 citations

Hyperuricemia, acute gout, renal insufficiency and urate nephrolithiasis due to starvation

1965 • 26 citations

Serum growth hormone and insulin in females without glucose intolerance

1969 • 25 citations

INACTIVITY AS A MAJOR FACTOR IN ADOLESCENT OBESITY

1965 • 25 citations

GROWTH-HORMONE RESPONSE TO ORAL GLUCOSE IN CHILDREN WITH SIMPLE OBESITY

1969 • 23 citations

Importance of Body Characteristics in the Excretion of 17-Ketosteroids and 17-Ketogenic Steroids in Obesity

1964 • 21 citations

CONTRAINDICATIONS AND THERAPEUTIC RESULTS OF FASTING IN OBESE PATIENTS*

1965 • 19 citations

Intussusception

1967 • 18 citations

Basal and stimulated insulin levels: Comparison of insulinogenic effects of oral glucose and intravenous tolbutamide in nondiabetic and diabetic subjects

1971 • 11 citations

Human energy expenditure in starvation estimated by expired-air analysis.

1967 • 8 citations

INSULIN RESPONSE TO GLUCAGON

1968 • 8 citations

Prevention of recurrent weight gain with large doses of synthetic thyroid hormones.

1970 • 6 citations

Effect of Diet on Malabsorption after Small Bowel By-Pass

1970 • 5 citations

Hydrocortisone and/or desiccated thyroid in physiologic dosage

1965 • 5 citations