Elevated binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methylcholanthrene to the Ah receptor in hepatic cytosols from phenobarbital-treated rats and mice

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol. Evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase.

1976 • 1,343 citations

Regulatory gene product of the Ah locus. Characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation.

1979 • 401 citations

Genetic Mechanisms Controlling the Induction of Polysubstrate Monooxygenase (P-450) Activities

1981 • 296 citations

Temperature-dependent cytosol-to-nucleus translocation of the Ah receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin in continuous cell culture lines.

1980 • 227 citations

Biochemical and genetic analysis of variant mouse hepatoma cells defective in the induction of benzo(a)pyrene-metabolizing enzyme activity.

1983 • 200 citations

The Ah locus: Correlation of intranuclear appearance of inducer-receptor complex with induction of cytochrome P1-450 mRNA

1982 • 184 citations

Principles of Drug Action

1995 • 170 citations

Regulatory gene product of the Ah locus. Characterization of receptor mutants among mouse hepatoma clones.

1982 • 160 citations

The induction of hepatic microsomal metabolism in rats following acute administration of a mixture of polybrominated biphenyls

1976 • 125 citations

Aryl Hydrocarbon Hydroxylase Induction in Mammalian Liver Cell Culture

1971 • 108 citations

Cytosolic and Nuclear Binding of 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin to the AhReceptor in Extra‐Hepatic Tissues of Rats and Mice

1982 • 103 citations

Selective Induction of Two Different Molecular Species of Cytochrome P-450 by Phenobarbital and 3-Methylcholanthrene

1981 • 95 citations

Regulatory gene product of the Ah complex. Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3-methylcholanthrene binding to several moieties in mouse liver cytosol.

1981 • 92 citations

Binding of 3-Methylcholanthrene and 2,3,7,8-Tetrachlorodibenzo-p-dioxin to a Common Ah Receptor Site in Mouse and Rat Hepatic Cytosols

1982 • 90 citations

Induction of hepatic mono-oxygenase systems in fetal and neonatal rats with phenobarbital, polycyclic hydrocarbons and other xenobiotics

1977 • 75 citations

Rapid vertical tube rotor gradient assay for binding of 2,3,7,8-tetrachIorodibenzo-p-dioxin to the Ah receptor

1981 • 73 citations

Ontogenetic Expression of Regulatory and Structural Gene Products Associated with the Ah Locus

1980 • 70 citations

Induction of both cytochromes P-450 and P-448 by 2,3′,4,4′,5-pentabromobiphenyl, a component of fireMaster

1980 • 56 citations

Induction of both 3-methylcholanthrene- and phenobarbitone-type microsomal enzyme activity by a single polychlorinated biphenyl isomer

1980 • 51 citations

Enhancement of Microsomal Drug Hydroxylation and Glucuronidation in Rat Liver by Phenobarbital and 3‐Methylcholanthrene in Combination

1974 • 37 citations

High-affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin in cell nuclei from rat liver

1982 • 31 citations

Effect of mixed and separate administration of phenobarbital and 3-methylcholanthrene on benzpyrene hydroxylase in the liver of sensitive and resistant inbred mice

1980 • 1 citations