Does the excitatory amino acid receptor antagonist 2-APH exhibit anxiolytic activity?

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

1985 • 5,596 citations

Glutamate: A Neurotransmitter in Mammalian Brain

1984 • 1,981 citations

Benzodiazepine receptors in rat brain

1977 • 1,459 citations

Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding.

1977 • 1,246 citations

Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of ?fear?-motivated behaviour

1984 • 951 citations

Anticonvulsant Action of Excitatory Amino Acid Antagonists

1982 • 692 citations

Interaction of Convulsive Ligands with Benzodiazepine Receptors

1982 • 549 citations

Protection against chemically induced seizures by 2-amino-7-phosphonoheptanoic acid

1982 • 258 citations

The benzodiazepine--GABA--chloride ionophore receptor complex: common site of minor tranquilizer action.

1981 • 170 citations

Binding Characteristics and Interactions of Depressant Drugs with [³⁵S]t-Butylbicyclophosphorothionate, a Ligand that Binds to the Picrotoxinin Site

1984 • 156 citations

Anticonvulsant action of 2-amino-7-phosphonoheptanoic acid in the substantia nigra

1984 • 124 citations

A new method for rapid screening of minor tranquillizers in mice

1968 • 124 citations

Antagonism of N-methyl-D,L-aspartic acid-induced convulsions by antiepileptic drugs and other agents

1985 • 117 citations

DMCM: A potent convulsive benzodiazepine receptor ligand

1983 • 109 citations

Muscle relaxant action of excitatory amino acid antagonists

1985 • 100 citations

Discriminative stimulus properties of ?-carbolines characterized as agonists and inverse agonists at central benzodiazepine receptors

1984 • 94 citations

A comparison of the anticonvulsant potency of (±) 2-amino-5-phosphono-pentanoic acid and (±) 2-amino-7-phosphonoheptanoic acid

1983 • 93 citations

?-Carbolines can enhance or antagonize the effects of punishment in mice

1985 • 82 citations

Pharmacological antagonists of excitant amino acid action

1981 • 77 citations