Randomized controlled trial of doxycycline in prevention of recurrent periodontitis in high-risk patients: antimicrobial activity and collagenase inhibition.

Periodontal Disease in Pregnancy II. Correlation Between Oral Hygiene and Periodontal Condition

1964 • 7,448 citations

Periodontal Disease in Pregnancy I. Prevalence and Severity

1963 • 6,901 citations

Clinical Trials: A Practical Approach.

1984 • 2,966 citations

An Assessment of Clinically Useful Measures of the Consequences of Treatment

1988 • 1,650 citations

A Long‐Term Survey of Tooth Loss in 600 Treated Periodontal Patients

1978 • 982 citations

Bacteroides gingivalis, Bacteroides intermedius and Actinobacillus actinomycetemcomitans in human periodontal diseases

1988 • 722 citations

Microbiology of Periodontal Disease—Present Status and Future Considerations

1977 • 643 citations

Tooth Loss in 100 Treated Patients With Periodontal Disease: A Long‐Term Study

1982 • 568 citations

Minocycline reduces gingival collagenolytic activity during diabetes

1983 • 415 citations

Recolonization of a subgingival microbiota following scaling in deep pockets

1984 • 378 citations

Periodontal Therapy in Humans: I. Microbiological and Clinical Effects of a Single Course of Periodontal Scaling and Root Planing, and of Adjunctive Tetracycline Therapy

1979 • 352 citations

Tetracyclines inhibit tissue collagenase activity

1984 • 318 citations

A Non-antibacterial Chemically-modified Tetracycline Inhibits Mammalian Collagenase Activity

1987 • 307 citations

Further evidence that tetracyclines inhibit collagenase activity in human crevicular fluid and from other mammalian sources

1985 • 215 citations

The effect of tetracycline and/or scaling on human periodontal disease

1979 • 205 citations

Antibiotics in the Treatment of Human Periodontal Diseases

1981 • 186 citations

Metronidazole in Periodontitis: I. Clinical and Bacteriological Results after 15 to 30 Weeks

1984 • 184 citations

The Effect of Long‐Term Low‐Dose Tetracycline Therapy on the Subgingival Microflora in Refractory Adult Periodontitis

1982 • 160 citations

Antibiotic Susceptibility of Anaerobic Bacteria from the Human Oral Cavity

1985 • 96 citations

Initial Characterization of a Neutral Metalloproteinase, Active on Native 3/4-Collagen Fragments, Synthesized by ROS 17/2.8 Osteoblastic Cells, Periodontal Fibroblasts, and Identified in Gingival Crevicular Fluid

1987 • 88 citations

Efficacy of Clindamycin Hydrochloride in Refractory Periodontitis: 12‐Month Results

1985 • 87 citations

Tetracycline: Levels Achievable in Gingival Crevice Fluid and in Vitro Effect on Subgingival Organisms: Part II. Susceptibilities of Periodontal Bacteria

1981 • 86 citations

Concentration of doxycycline in human gingival fluid

1986 • 84 citations

Combined antibiotic (metronidazole) and mechanical treatment effects on the subgingival bacterial flora of sites with recurrent periodontal disease

1988 • 71 citations

Tetracycline: A Clinical Study to Determine its Effectiveness as Long‐Term Adjuvant

1980 • 49 citations

Identification of matrix metalloendoproteinase inhibitor (TIMP) in human parotid and submandibular saliva: partial purification and characterization

1988 • 45 citations

A highly sensitive and specific assay for vertebrate collagenase

1981 • 29 citations

Antibiotics and Periodontal Disease: A Selective Review of the Literature

1982 • 14 citations

Tricks and traps in dental clinical trials

1985 • 9 citations