Protective effect of WEB 2086, a novel antagonist of platelet activating factor, in endotoxin shock

LEUKOCYTE-DEPENDENT HISTAMINE RELEASE FROM RABBIT PLATELETS

1972 • 1,214 citations

The release of platelet-activating factor from human endothelial cells in culture.

1983 • 436 citations

Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate.

1985 • 430 citations

BACKGROUND AND PRESENT STATUS OF RESEARCH ON PLATELET‐ACTIVATING FACTOR (PAF‐ACETHER)

1981 • 332 citations

Platelet activating factor (PAF) involvement in endotoxin-induced hypotension in rats. studies with paf-receptor antagonist kadsurenone

1985 • 298 citations

Is platelet activating factor (PAF) a mediator of endotoxin shock?

1985 • 247 citations

Elevated Thromboxane Levels in the Rat during Endotoxic Shock

1980 • 245 citations

Lipopolysaccharide-mediated bovine endothelial cell injury in vitro.

1983 • 215 citations

Biosynthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet activating factor and a hypotensive lipid) by cholinephosphotransferase in various rat tissues

1981 • 200 citations

Platelet‐Activating Factor (PAF‐Acether) Secretion from Platelets: Effect of Aggregating Agents

1980 • 195 citations

Vascular actions of synthetic PAF-acether (a synthetic platelet-activating factor) in the rat: Evidence for a platelet independent mechanism

1982 • 138 citations

Endotoxin-induced prostaglandin E and F release in dogs

1975 • 116 citations

Structural identification of platelet activating factor in psoriatic scale

1985 • 110 citations

Synthesis of PAF-acether and blood volume changes in gram-negative sepsis

1985 • 109 citations

Platelet-activating factor (PAF-acether) and macrophages

1981 • 74 citations

Release of platelet-activating factor (PAF-acether) and 2-lyso PAF-acether from three cell types

1982 • 60 citations

Cardiac, coronary and peripheral vascular effects of acetyl glyceryl ether phosphoryl choline in the anesthetized dog.

1985 • 59 citations

Change in membrane lipid fluidity induced by phospholipase a activation: A mechanism of endotoxic shock

1983 • 46 citations

Interference of BN 52021, a paf-acether antagonist, with endotoxin-induced hypotension in the guinea-pig

1986 • 46 citations

Unilateral Shwartzman reaction: Cortical necrosis in one kidney following in vivo perfusion with endotoxin

1977 • 42 citations

Prostacyclin and thromboxane A2 in septic shock: species differences.

1986 • 29 citations

Interaction of platelets with bacterial endotoxins

1983 • 14 citations

Pulmonary microvascular permeability following E. coli endotoxin and hemorrhage

1982 • 14 citations

Experimental endotoxemia in the rat: efficacy of prostacyclin or the prostacyclin analog iloprost.

1985 • 8 citations