Deoxyribose breakdown by the adriamycin semiquinone and H₂O₂: evidence for hydroxyl radical participation

Superoxide‐dependent production of hydroxyl radical catalyzed by iron—EDTA complex

1978 • 876 citations

Formation of a thiobarbituric‐acid‐reactive substance from deoxyribose in the presence of iron salts

1981 • 830 citations

Superoxide‐dependent formation of hydroxyl radicals in the presence of iron chelates

1978 • 748 citations

Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycin

1977 • 545 citations

NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals.

1979 • 492 citations

Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage.

1981 • 415 citations

Anthracycline antibiotic augmentation of microsomal electron transport and free radical formation.

1977 • 365 citations

Thiobarbituric acid‐reactivity following iron‐dependent free‐radical damage to amino acids and carbohydrates

1981 • 284 citations

Reduction of adriamycin to a semiquinone-free radical by NADPH cytochrome P-450 reductase produces DNA cleavage in a reaction mediated by molecular oxygen.

1981 • 275 citations

Strand scission of DNA by bound adriamycin and daunorubicin in the presence of reducing agents

1977 • 258 citations

Adriamycin stimulated superoxide formation in submitochondrial particles

1977 • 256 citations

Hydroxyl radical production in body fluids Roles of metal ions, ascorbate and superoxide

1981 • 250 citations

Oxygen species in paraquat toxicity: the crypto‐OH radical

1981 • 149 citations

Ethylene from 2-keto-4-thiomethyl butyric acid: The Haber-Weiss reaction

1980 • 88 citations

Evidence for the production of hydroxyl radicals from the adriamycin semiquinone and H₂O₂

1981 • 83 citations

Evidence for the generation of free hydroxyl radicals from certain quinone antitumor antibiotics upon reductive activation in solution

1981 • 69 citations

Identification of malondialdehyde as the TBA‐reactant formed by bleomycin‐iron free radical damage to DNA

1979 • 54 citations

Reactions of Adriamycin with haemoglobin. Superoxide dismutase indirectly inhibits reactions of the Adriamycin semiquinone

1982 • 43 citations