Longitudinal changes in cognition and behavior in asymptomatic carriers of the APOE e4 allele

Clinical diagnosis of Alzheimer's disease

1984 • 27,279 citations

Current Concepts in Mild Cognitive Impairment

2001 • 4,609 citations

Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI.

1990 • 2,936 citations

Population-Based Norms for the Mini-Mental State Examination by Age and Educational Level

1993 • 2,707 citations

Practice parameter: Early detection of dementia: Mild cognitive impairment (an evidence-based review) [RETIRED]

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Mild Cognitive Impairment Represents Early-Stage Alzheimer Disease

2001 • 1,786 citations

Preclinical Evidence of Alzheimer's Disease in Persons Homozygous for the ε4 Allele for Apolipoprotein E

1996 • 1,320 citations

Participation in Cognitively Stimulating Activities and Risk of Incident Alzheimer Disease

2002 • 1,297 citations

Patterns of Brain Activation in People at Risk for Alzheimer's Disease

2000 • 1,282 citations

Age‐associated memory impairment: Proposed diagnostic criteria and measures of clinical change — report of a national institute of mental health work group

1986 • 928 citations

Influence of leisure activity on the incidence of Alzheimer’s Disease

2001 • 793 citations

Apolipoprotein E Type 4 Allele and Cerebral Glucose Metabolism in Relatives at Risk for Familial Alzheimer Disease

1995 • 575 citations

Declining brain activity in cognitively normal apolipoprotein E ɛ4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease

2001 • 453 citations

Cognitive activity and incident AD in a population-based sample of older persons

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Patients with Alzheimer's disease have reduced activities in midlife compared with healthy control-group members

2001 • 431 citations

Personality Assessment Inventory

1991 • 354 citations

Altered brain activation in cognitively intact individuals at high risk for Alzheimer’s disease

1999 • 202 citations

A twin study of late-onset depression and apolipoprotein E ε4 as risk factors for alzheimer's disease

1997 • 168 citations

High Frequency of Apolipoprotein E ϵ4 Allele in Young Individuals with Very Mild Alzheimer's Disease-Related Neurofibrillary Changes

1998 • 132 citations

Preclinical memory decline in cognitively normal apolipoprotein E–ε4 homozygotes

1999 • 126 citations

Longitudinal follow‐up of depressive symptoms among normal versus cognitively impaired elderly

2001 • 103 citations

Neuropathology of preclinical and clinical lateonset Alzheimer's disease

1998 • 91 citations

Apolipoprotein E ε4 affects new learning in cognitively normal individuals at risk for Alzheimer’s disease

2003 • 68 citations

Early-Onset and Late-Onset Depression Are Independent of the Genetic Polymorphism of Apolipoprotein E

1999 • 67 citations

Preclinical cognitive decline in late middle-aged asymptomatic apolipoprotein E-e4/4 homozygotes: a replication study

2001 • 64 citations

A Distinctive Interaction Between Chronic Anxiety and Problem Solving in Asymptomatic APOE e4 Homozygotes

2004 • 50 citations

A Longitudinal Study of Apolipoprotein-E Genotype and Depressive Symptoms in Community-Dwelling Older Adults

2000 • 49 citations

Depression and dementia in relation to apolipoprotein E polymorphism in a population sample age 75+

1997 • 47 citations

A Distinctive Interaction Between Memory and Chronic Daytime Somnolence in Asymptomatic APOE e4 Homozygotes

2002 • 39 citations

Factors associated with depressive symptoms in non-demented community-dwelling elderly

1999 • 33 citations

Association of Angiotensin-Converting Enzyme Gene Polymorphism with Lipid Profiles in Children and Adolescents with Insulin-Dependent Diabetes mellitus

1999 • 18 citations