Nucleotide sequence and transcriptional analysis of molecular clones of CAEV which generate infectious virus

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1983 • 6,811 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

Prediction of protein antigenic determinants from amino acid sequences.

1981 • 3,715 citations

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1984 • 3,647 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

On Finding All Suboptimal Foldings of an RNA Molecule

1989 • 2,019 citations

The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA

1989 • 1,280 citations

New hydrophilicity scale derived from high-performance liquid chromatography peptide retention data: correlation of predicted surface residues with antigenicity and x-ray-derived accessible sites

1986 • 1,150 citations

Improved predictions of secondary structures for RNA.

1989 • 822 citations

Automation of the computer handling of gel reading data produced by the shotgun method of DNA sequencing

1982 • 744 citations

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

1989 • 742 citations

Detection of lymphocytes expressing human T-lymphotropic virus type III in lymph nodes and peripheral blood from infected individuals by in situ hybridization.

1986 • 740 citations

Surface and inside volumes in globular proteins

1979 • 704 citations

Signals for ribosomal frameshifting in the rous sarcoma virus gag-pol region

1988 • 617 citations

Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus

1985 • 572 citations

The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization

1989 • 400 citations

Chronic Arthritis in Goats Caused by a Retrovirus

1980 • 395 citations

Translation Initiation at Non-Aug Triplets in Mammalian Cells

1989 • 363 citations

Slow Virus Replication: the Role of Macrophages in the Persistence and Expression of Visna Viruses of Sheep and Goats

1982 • 283 citations

Visna, a Demyelinating Transmissible Disease of Sheep

1957 • 281 citations

Infectious Leukoencephalomyelitis of Young Goats

1974 • 262 citations

Activation of caprine arthritis-encephalitis virus expression during maturation of monocytes to macrophages

1983 • 240 citations

Los Alamos sequence analysis package for nucleic acids and proteins

1982 • 233 citations

Nucleotide sequence analysis of feline immunodeficiency virus: genome organization and relationship to other lentiviruses.

1989 • 227 citations

Lipid Linked Sugars in Glycoprotein Synthesis

1975 • 201 citations

Biological Characterization of the Virus Causing Leukoencephalitis and Arthritis in Goats

1980 • 193 citations

Secondary Structure is the Major Determinant for Interaction of HIV rev Protein with RNA

1990 • 188 citations

Antigenic Shift of Visna Virus in Persistently Infected Sheep

1977 • 181 citations

Site-Directed Mutagenesis of Two Trans-Regulatory Genes ( tat -III, trs ) of HIV-1

1988 • 180 citations

Direct mapping of adeno-associated virus capsid proteins B and C: a possible ACG initiation codon.

1985 • 173 citations

Sequence comparisons of retroviral proteins: relative rates of change and general phylogeny.

1988 • 169 citations

Functional Analysis of CAR, the Target Sequence for the Rev Protein of HIV-1

1989 • 152 citations

Nucleotide sequence analysis of SA-OMVV, a visna-related ovine lentivirus: phylogenetic history of lentiviruses

1990 • 135 citations

Virus Mutation during 'Slow Infection': Temporal Development and Characterization of Mutants of Visna Virus recovered from Sheep

1978 • 129 citations

Visna of sheep; a slow, demyelinating infection.

1958 • 129 citations

The visna virus genome: evidence for a hypervariable site in the env gene and sequence homology among lentivirus envelope proteins

1987 • 123 citations

Energy directed folding of RNA sequences

1984 • 99 citations

Lack of neutralizing antibodies to caprine arthritis-encephalitis lentivirus in persistently infected goats can be overcome by immunization with inactivated Mycobacterium tuberculosis

1984 • 98 citations

Use of statistical criteria for screening potential homologies in nucleic acid sequences

1984 • 95 citations

Sequences in the visna virus long terminal repeat that control transcriptional activity and respond to viral trans-activation: involvement of AP-1 sites in basal activity and trans-activation

1989 • 93 citations

A highly conserved RNA folding region coincident with the Rev response element of primate immunodeficiency viruses

1990 • 88 citations

Preferential immune response to virion surface glycoproteins by caprine arthritis-encephalitis virus-infected goats

1983 • 82 citations

Regulation of the visna virus long terminal repeat in macrophages involves cellular factors that bind sequences containing AP-1 sites.

1989 • 80 citations

Sequence homology between cloned caprine arthritis encephalitis virus and visna virus, two neurotropic lentiviruses

1986 • 75 citations

Nucleotide sequence and transcriptional activity of the caprine arthritis-encephalitis virus long terminal repeat

1986 • 71 citations

Characterization of a cDNA clone encoding the visna virus transactivating protein.

1989 • 63 citations

Visna virus encodes a post-transcriptional regulator of viral structural gene expression.

1990 • 60 citations

Visna virus exhibits a complex transcriptional pattern: one aspect of gene expression shared with the acquired immunodeficiency syndrome retrovirus

1987 • 52 citations

Neutralizing antibody response of rabbits and goats to caprine arthritis-encephalitis virus

1982 • 51 citations

Molecular cloning of integrated caprine arthritis-encephalitis virus

1985 • 46 citations

Genomic changes associated with antigenic variation of visna virus

1982 • 43 citations

Regulation of the Visna Virus Long Terminal Repeat in Macrophages Involves Cellular Factors That Bind Sequences Containing AP-1 Sites

1989 • 29 citations

Evolution of the primary and secondary structures of the E1a mRNAs of the adenovirus.

1987 • 22 citations

A multiple alignment program for protein sequences

1987 • 16 citations

Visna virus encodes a post-transcriptional regulator of viral structural gene expression

1990 • 10 citations