EFFECTS OF SYNVINOLIN (MK-733) ON PLASMA LIPIDS IN FAMILIAL HYPERCHOLESTEROLAEMIA

Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge

1972 • 31,801 citations

Serum Cholesterol, Lipoproteins, and the Risk of Coronary Heart Disease

1971 • 2,055 citations

Cholesterol determination in high-density lipoproteins separated by three different methods.

1977 • 1,857 citations

Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

1980 • 1,607 citations

Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth.

1980 • 1,195 citations

The Lipid Research Clinics Coronary Primary Prevention Trial results. I. Reduction in incidence of coronary heart disease

1984 • 764 citations

RISKS OF ISCHÆMIC HEART-DISEASE IN FAMILIAL HYPERLIPOPROTEINÆMIC STATES

1969 • 623 citations

Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes.

1983 • 562 citations

Diet, Lipoproteins, and the Progression of Coronary Atherosclerosis

1985 • 494 citations

Defective Lipoprotein Receptors and Atherosclerosis

1983 • 469 citations

Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog.

1981 • 424 citations

Effects of an Inhibitor of 3-Hydroxy-3-Methylglutaryl Coenzyme a Reductase on Serum Lipoproteins and Ubiquinone-10 Levels in Patients with Familial Hypercholesterolemia

1981 • 262 citations

Therapeutic effects of ML-236B in primary hypercholesterolemia

1980 • 231 citations

A study of the use of polyethylene glycol in estimating cholesterol in high-density lipoprotein.

1980 • 218 citations

Influence of mevinolin on metabolism of low density lipoproteins in primary moderate hypercholesterolemia.

1985 • 210 citations

Cholesterol-lowering effect of mevinolin, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme a reductase, in healthy volunteers.

1982 • 206 citations

Reduction of Serum Cholesterol in Heterozygous Patients with Familial Hypercholesterolemia

1983 • 201 citations

Normalization of Low-Density-Lipoprotein Levels in Heterozygous Familial Hypercholesterolemia with a Combined Drug Regimen

1981 • 197 citations

Hypocholesterolemic effects of mevinolin in patients with heterozygous familial hypercholesterolemia.

1984 • 176 citations

Diet, Lipoproteins and the Progression of Coronary Atherosclerosis

1986 • 148 citations

Mevinolin Plus Colestipol in Therapy for Severe Heterozygous Familial Hypercholesterolemia

1984 • 132 citations

Manual and Semi-Automated Procedures for Measurement of Triglycerides in Serum

1975 • 114 citations

Influence of Combined Therapy with Mevinolin and Interruption of Bile-Acid Reabsorption on Low Density Lipoproteins in Heterozygous Familial Hypercholesterolemia

1985 • 108 citations

Five methods for determining low-density lipoprotein cholesterol compared.

1984 • 104 citations

Effectiveness of mevinolin on plasma lipoprotein concentrations in type II hyperlipoproteinemia

1986 • 86 citations

Familial Hypercholesterolemia

1982 • 58 citations

An improved semi-automated method for the colorimetric determination of triglycerides in serum

1975 • 37 citations