Effect of Chronic Desipramine Treatment on Dihydroalprenolol, Imipramine, and Desipramine Binding Sites: A Quantitative Autoradiographic Study in the Rat Brain

Development of β-adrenergic receptor subsensitivity by antidepressants

1977 • 727 citations

High-Affinity [ ³ H]Imipramine Binding in Rat Hypothalamus: Association with Uptake of Serotonin But Not of Norepinephrine

1980 • 378 citations

Quantitative autoradiography of beta 1- and beta 2-adrenergic receptors in rat brain.

1984 • 349 citations

Demonstration of specific high affinity binding sites for [3H] imipramine in human brain

1980 • 258 citations

Specific tricyclic antidepressant binding sites in rat brain characterised by high-affinity 3H-imipramine binding

1980 • 249 citations

Adrenergic and serotonergic receptor binding in rat brain after chronic desmethylimipramine treatment.

1979 • 211 citations

Quantitative receptor autoradiography with tritium-labeled ligands: comparison of biochemical and densitometric measurements

1984 • 155 citations

Beta-Adrenergic-Receptor Localization by Light Microscopic Autoradiography

1980 • 150 citations

Antidepressants: Neurochemical, Behavioral, and Clinical Perspectives

1982 • 116 citations

Electroconvulsive Shock and Reserpine: Effects on β‐Adrenergic Receptors in Rat Brain

1981 • 104 citations

Regional distribution of [3H]imipramine binding in rat brain

1981 • 96 citations

Down regulation of dihydroalprenolol and imipramine binding sites in brain of rats repeatedly treated with imipramine

1980 • 95 citations

Norepinephrine neuronal uptake binding sites in rat brain membranes labeled with [3H]desipramine.

1981 • 93 citations

High‐Affinity Binding of [3H]Desipramine to Rat Brain: A Presynaptic Marker for Noradrenergic Uptake Sites

1982 • 85 citations

Concomitant decrease in [3H]imipramine binding in cat brain and platelets after chronic treatment with imipramine

1982 • 75 citations

Localization and characterization of [3H]desmethylimipramine binding sites in rat brain by quantitative autoradiography

1983 • 74 citations

‘High affinity’ binding of [3H] desipramine to rat cerebral cortex: Relationship to tricyclic antidepressant-induced inhibition of norepinephrine uptake

1981 • 59 citations

3H-imipramine high-affinity binding sites in rat brain. Effects of imipramine and lithium

1982 • 58 citations

Selective changes in the density of ß1-adrenergic receptors in rat striatum following chronic drug treatment and adrenalectomy

1982 • 35 citations

Distribution of imipramine binding sites in the rat brain studied by quantitative autoradiography

1983 • 30 citations

An inexpensive microcomputer-based image-analysis system: novel applications to quantitative autoradiography

1985 • 27 citations

The in vivo distribution of an antidepressant drug (DMI) in male and female rats

1979 • 27 citations

Effect of chronic desmethylimipramine or electroconvulsive shock on selected brain and platelet neurotransmitter recognition sites

1985 • 23 citations

Quantitative autoradiography of neurochemicals

1982 • 17 citations

Age alters the observed response of imipramine binding sites to chronic antidepressant treatment in female rats

1984 • 13 citations