Molecular and population genetic analysis of allelicsequence diversity at the human beta-globin locus.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

On the number of segregating sites in genetical models without recombination

1975 • 3,989 citations

Mitochondrial DNA and human evolution

1987 • 2,967 citations

Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)

1989 • 2,480 citations

A Test of Neutral Molecular Evolution Based on Nucleotide Data

1987 • 1,789 citations

Evolution of genes and proteins.

1983 • 1,224 citations

Effects of primer-template mismatches on the polymerase chain reaction: Human immunodeficiency virus type 1 model studies

1990 • 1,037 citations

Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β-globin gene cluster

1982 • 937 citations

Nucleotide polymorphism at the alcohol dehydrogenase locus of Drosophila melanogaster

1983 • 707 citations

Low nucleotide diversity in man.

1991 • 501 citations

Drift, admixture, and selection in human evolution: a study with DNA polymorphisms.

1991 • 413 citations

Nonrandom association of polymorphic restriction sites in the β-globin gene cluster

1982 • 408 citations

Polymerase chain reaction amplification applied to the determination of β‐like globin gene cluster haplotypes

1989 • 317 citations

Allelic genealogy and human evolution.

1993 • 293 citations

Evolutionary relationships of human populations from an analysis of nuclear DNA polymorphisms

1986 • 253 citations

Average Number of Nucleotide Differences in a Sample From a Single Subpopulation: A Test for Population Subdivision

1987 • 253 citations

DNA polymorphism and molecular pathology of the human globin gene clusters

1985 • 251 citations

The Z-DNA motif d(TG)30 promotes reception of information during gene conversion events while stimulating homologous recombination in human cells in culture.

1990 • 147 citations

The colonization of the pacific: A genetic trail

1990 • 146 citations

Nucleotide sequence analysis of the delta beta-globin gene region in humans.

1983 • 144 citations

Why are some genetic diseases common?

1993 • 131 citations

A novel sickle cell mutation of yet another origin in Africa: the Cameroon type

1992 • 120 citations

The silent carrier allele: β thalassemia without a mutation in the β-globin gene or its immediate flanking regions

1984 • 89 citations

Structural analysis of the 5' flanking region of the beta-globin gene in African sickle cell anemia patients: further evidence for three origins of the sickle cell mutation in Africa.

1988 • 85 citations

Improved yields of long PCR products using gene 32 protein

1990 • 82 citations

THE EFFECT OF INTRAGENIC RECOMBINATION ON THE NUMBER OF ALLELES IN A FINITE POPULATION

1978 • 70 citations

The DNA sequence of the 5′ flanking region of the human 0-gk bin gene: evolutionary conservation and polymorphic differences

1982 • 69 citations

Beta thalassemia in Melanesia: association with malaria and characterization of a common variant (IVS-1 nt 5 G----C)

1988 • 57 citations

Origin and spread of beta-globin gene mutations in India, Africa, and Mediterranea: analysis of the 5' flanking and intragenic sequences of beta S and beta C genes.

1991 • 57 citations

Evolution of the primate β-globin gene region

1985 • 55 citations

Phylogenetic analysis of polymorphic DNA sequences at the Adh locus inDrosophila melanogaster and its sibling species

1985 • 54 citations

The Z-DNA Motif d(TG)₃₀ Promotes Reception of Information during Gene Conversion Events while Stimulating Homologous Recombination in Human Cells in Culture

1990 • 49 citations

Detection of a novel DNA polymorphism in the beta-globin gene cluster.

1984 • 42 citations

Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae.

1991 • 31 citations

Molecular applications in biological anthropology

1993 • 27 citations

Polymorphism of the Hinf I restriction site located 1 Kb 5? to the human ?-globin gene

1982 • 8 citations