c-kit mutations in gastrointestinal stromal tumours

Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors

1998 • 4,380 citations

Effect of the Tyrosine Kinase Inhibitor STI571 in a Patient with a Metastatic Gastrointestinal Stromal Tumor

2001 • 2,038 citations

GROWTH FACTOR RECEPTOR TYROSINE KINASES

1988 • 1,841 citations

Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal.

1998 • 1,674 citations

Lessons learned from the development of an Abl tyrosine kinase inhibitor for chronic myelogenous leukemia

2000 • 897 citations

Requirement of c-kit for development of intestinal pacemaker system

1992 • 700 citations

KIT Extracellular and Kinase Domain Mutations in Gastrointestinal Stromal Tumors

2000 • 648 citations

Prognosis of Gastrointestinal Smooth-Muscle (Stromal) Tumors

1999 • 629 citations

Interstitial Cells of Cajal as Precursors of Gastrointestinal Stromal Tumors

1999 • 567 citations

Mutations in Exon 11 of c-Kit Occur Preferentially in Malignant versus Benign Gastrointestinal Stromal Tumors and Do Not Occur in Leiomyomas or Leiomyosarcomas

1999 • 555 citations

Gastrointestinal Stromal Tumors/Smooth Muscle Tumors (GISTs) Primary in the Omentum and Mesentery

1999 • 508 citations

Esophageal Stromal Tumors

2000 • 471 citations

Effect of c-kit Mutation on Prognosis of Gastrointestinal Stromal Tumors

2001 • 437 citations

Differentiation and Risk Assessment of Gastrointestinal Stromal Tumors

1995 • 319 citations

KIT mutation portends poor prognosis in gastrointestinal stromal/smooth muscle tumors.

1998 • 246 citations

Mastocytosis: recent advances in defining the disease

2001 • 176 citations

Molecular Insights into the Histogenesis and Pathogenesis of Gastrointestinal Stromal Tumors

2000 • 174 citations

Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumors

1999 • 166 citations

C‐kit Gene Abnormalities in Gastrointestinal Stromal Tumors (Tumors of Interstitial Cells of Cajal)

1999 • 132 citations

Restriction Endonuclease-Mediated Selective Polymerase Chain Reaction

1998 • 76 citations

Loss of heterozygosity at 1p36 predicts poor prognosis in gastrointestinal stromal/smooth muscle tumors.

1999 • 60 citations

Gastrointestinal Stromal Tumor, Uncommitted Type, with Monosomies 14 and 22 as the Only Chromosomal Abnormalities

1998 • 26 citations