Effects of Captopril in Animal Models of Hypertension

Development of a Strain of Spontaneously Hypertensive Rats

1963 • 2,492 citations

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

1977 • 1,851 citations

Antihypertensive Effect of the Oral Angiotensin Converting-Enzyme Inhibitor SQ 14225 in Man

1978 • 612 citations

Clinical experience with blockade of the renin-angiotensin-aldosterone system by an oral converting-enzyme inhibitor (SQ 14,225, captopril) in hypertensive patients

1978 • 364 citations

Oral Angiotensin-Converting Enzyme Inhibitor in Long-Term Treatment of Hypertensive Patients

1979 • 357 citations

Role of the Pressor Action of Angiotensin IIin Experimental Hypertension

1971 • 297 citations

Converting enzyme inhibition with an orally active compound in hypertensive man.

1979 • 224 citations

SQ 14,225 (D-3-mercapto-2-methylpropanoyl-l-proline), a novel orally active inhibitor of angiotensin I-converting enzyme.

1978 • 209 citations

Interruption of the renin-angiotensin system in hypertensive patients by captopril induces sustained reduction in aldosterone secretion, potassium retention and natruiresis.

1979 • 185 citations

Antihypertensive activity in rats for SQ 14,225, an orally active inhibitor of angiotensin I-converting enzyme.

1978 • 172 citations

Altered Urinary Kallikrein Excretion in Rats with Hypertension

1972 • 150 citations

Haemodynamics of Orally-Active Converting Enzyme Inhibitor (SQ 14225) in Hypertensive Patients

1978 • 147 citations

THE ISO-RENIN ANGIOTENSIN SYSTEMS IN EXTRARENAL TISSUE

1976 • 145 citations

Renin in Rats with Spontaneous Hypertension

1972 • 132 citations

Inactivation of bradykinin in the pulmonary circulation

1968 • 127 citations

Captopril (SQ 14,225) (d-3-mercapto-2-methylpropanoyl-l-proline): A novel orally active inhibitor of angiotensin-converting enzyme and antihypertensive agent

1978 • 114 citations

Renin-angiotensin system in spontaneously hypertensive rats

1976 • 100 citations

Renin Release, Saralasin and the Vasodilator-Beta-Blocker Drug Interaction in Man

1975 • 99 citations

EFFECTS OF CHRONIC TREATMENT WITH CAPTOPRIL(SQ 14,225), AN ORALLY ACTIVE INHIBITOR OFANGIOTENSIN I-CONVERTING ENZYME, INSPONTANEOUSLY HYPERTENSIVE RATS

1979 • 94 citations

Arterial Wall or Plasma Renin in Hypertension?

1979 • 86 citations

Inhibition of angiotensin converting enzyme by SQ 14,225 in conscious rabbits

1977 • 79 citations

Hemodynamic and antihypertensive effects of captopril, an orally active angiotensin converting enzyme inhibitor.

1979 • 78 citations

AN IN VIVO ESTIMATION OF THE POTENCIES AND HALF-LIVES OF SYNTHETIC BRADYKININ AND KALLIDIN.

1965 • 69 citations

Chronic antihypertensive effects of captopril (SQ 14,225), an orally active angiotensin I-converting enzyme inhibitor, in conscious 2-kidney renal hypertensive rats

1978 • 62 citations

Hypotension induced by inhibition of angiotensin-converting enzyme in pentobarbital-anesthetized dogs

1978 • 53 citations

Effects of angiotensen antagonist in rats with acute, subacute, and chronic two-kidney renal hypertension.

1978 • 52 citations

Role of renin-angiotensin system in chronic renal hypertensive rats.

1979 • 50 citations

Inhibition of Angiotensin-Converting Enzyme by SQ 14,225 in Anesthetized Dogs: Hernodynamic and Renal Vascular Effects

1978 • 49 citations

Effects of SQ 14,225, an orally active inhibitor of angiotensin-converting enzyme on blood pressure, heart rate and plasma renin activity of conscious normotensive dogs

1978 • 39 citations

Experimental Studies on the Relationship between Endocrine Organs and Hypertension in Spontaneously Hypertensive Rats

1964 • 30 citations

Factors determining the success or failure of nephrectomy in experimental renal hypertension.

1970 • 30 citations

Effects of the Oral Converting Enzyme Inhibitor (SQ 14225) on One-Kidney Hypertension in the Dog

1978 • 27 citations

Relation of Renal Arterial Pressure to Activity of Renin-Angiotensin System in Renal Hypertension.

1967 • 26 citations

Long-Term Efficacy of Captopril (SQ 14,225) In 2-Kidney Renal Hypertensive Rats

1979 • 20 citations

Blood Pressure Response and Antibody Formation in Spontaneously-Hypertensive Rats and Normal Albino Rats after Immunization against Angiotensin II*

1972 • 19 citations

Response to Saralasin and Angiotensinʼs Role in Essential and Renal Hypertension

1979 • 18 citations

Interrelations of Renin, Angiotensin II, and Sodium in Hypertension and Renal Failure

1976 • 17 citations

Neurogenic Activity–Angiotensin II Interaction during the Development and Maintenance of Renal Hypertension in the Rat

1979 • 15 citations

Synthetic Phosphatidylethanolamines as Renin Inhibitors

1977 • 12 citations

Antagonists, inhibitors and antisera in the evaluation of vascular renin activity. The role of local generation of angiotensin II.

1976 • 7 citations