The pattern of methylated purines formed in DNA of intact and regenerating liver of rats treated with the carcinogen dimethylnitrosamine

Experimental pathology of the liver

1931 • 3,113 citations

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1969 • 949 citations

FURTHER STUDIES ON THE ALKYLATION OF NUCLEIC ACIDS AND THEIR CONSTITUENT NUCLEOTIDES

1963 • 801 citations

Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N′-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

1970 • 500 citations

Toxic liver injury and carcinogenesis. Methylation of rat-liver nucleic acids by dimethylnitrosamine in vivo

1962 • 399 citations

Nitrosamine-induced carcinogenesis. The alkylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate

1968 • 378 citations

Effects of Some Chemical Mutagens and Carcinogens on Nucleic Acids

1966 • 370 citations

Essential Chemical Requirements for Induction of Allergic Encephalomyelitis

1971 • 195 citations

Methylation of ribonucleic acid by the carcinogens dimethyl sulphate, N-methyl-N-nitrosourea and N-methyl-N′-nitro-N-nitrosoguanidine. Comparisons of chemical analyses at the nucleoside and base levels

1972 • 185 citations

Specific excision of methylation products from DNA of Escherichia coli treated with N-methyl-N′-nitro-N-nitrosoguanidine

1970 • 173 citations

A Method for the Rapid Isolation of Nuclear Membranes from Rat Liver

1972 • 147 citations

Repair of Alkylated DNA in Mammalian Cells

1968 • 124 citations

THE NUCLEIC ACIDS OF SOME INSECT VIRUSES

1952 • 114 citations

Inactivation and mutation of coliphage T2 by N-methyl- and N-ethyl-N-nitrosourea

1969 • 109 citations

Ribonucleic acids II. Improved preparation of rat-liver ribonucleic acid

1962 • 104 citations

The Properties of 7-Methylguanine-containing Templates for Ribonucleic Acid Polymerase

1970 • 97 citations

REACTION OF THE CARCINOGEN DIMETHYLNITROSAMINE WITH NUCLEIC ACIDS IN VIVO

1963 • 95 citations

Liver regeneration and induction of hepatomas in B6AF mice by urethan.

1970 • 78 citations

Reaction of alkylating mutagens and carcinogens with nucleic acids: detection and estimation of a small extent of methylation at O-6 of guanine in DNA by methyl methanesulphonate in vitro

1972 • 77 citations

Chemical Carcinogenesis in Infant Animals

2015 • 73 citations

DNA Synthesis associated with the Inner Membrane of the Nuclear Envelope

1971 • 69 citations

7,12-Dimethylbenz(α)anthracene and hepatic neoplasia in regenerating rat liver

1970 • 65 citations

The covalent binding of metabolites of tritiated 2-methyl-4-dimethylaminoazobenzene to rat liver nucleic acids and proteins, and the carcinogenicity of the unlabelled compound in partially hepatectomised rats

1967 • 61 citations

Increased susceptibility to low doses of a carcinogen of epidermal cells in stimulated DNA synthesis.

1967 • 59 citations

Enhancement of Urethan Induction of Hepatomas in Mice by Prior Partial Hepatectomy

1968 • 54 citations

Methylation of nuclear proteins by dimethylnitrosamine and by methionine in the rat in vivo

1971 • 53 citations

Methylated bases in liver nucleic acids from rats treated with dimethylnitrosamine

1968 • 45 citations

Stability of deoxyribonucleic acid methylated in the intact animal by administration of dimethylnitrosamine. Rate of breakdown in vivo and in vitro at different dosages

1969 • 45 citations

Differences in the patterns of methylation in rat liver ribosomal ribonucleic acid after reaction in vivo with methyl methanesulphonate and NN-dimethylnitrosamine

1972 • 39 citations

Occurrence of 7-methylguanine in nucleic acids of rat liver

1968 • 28 citations

Alkylation of polynucleotide complexes

1965 • 23 citations

Analysis of DNA for the formation of 3-methylthymine after administration of dimethylnitrosamine

1972 • 9 citations