Effects of Telomerase and Telomere Length on Epidermal Stem Cell Behavior

Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA

1997 • 2,086 citations

Switching and Signaling at the Telomere

2001 • 2,073 citations

Defining the Epithelial Stem Cell Niche in Skin

2003 • 1,995 citations

Self-Renewal, Multipotency, and the Existence of Two Cell Populations within an Epithelial Stem Cell Niche

2004 • 1,387 citations

Three clonal types of keratinocyte with different capacities for multiplication.

1987 • 1,271 citations

Essential role of mouse telomerase in highly proliferative organs

1998 • 1,256 citations

Protection of mammalian telomeres

2002 • 926 citations

Self-renewal and solid tumor stem cells

2004 • 894 citations

Senescence and immortalization: role of telomeres and telomerase

2004 • 699 citations

Telomerase in the human organism

2002 • 594 citations

Telomeres, stem cells, senescence, and cancer

2004 • 480 citations

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

1999 • 462 citations

Manipulation of stem cell proliferation and lineage commitment:visualisation of label-retaining cells in wholemounts of mouse epidermis

2003 • 420 citations

Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes

2001 • 374 citations

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis

2000 • 346 citations

Stem-cell hierarchy in skin cancer

2003 • 271 citations

The role of stem cells in aging

2003 • 192 citations

Telomerase beyond telomeres

2002 • 174 citations

Telomere shortening and chromosomal instability abrogates proliferation of adult but not embryonic neural stem cells

2004 • 148 citations

Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles

1994 • 139 citations

Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells

2002 • 135 citations

Mammalian telomeres and telomerase: why they matter for cancer and aging

2003 • 104 citations

Stem cells, aging, and cancer: inevitabilities and outcomes

2004 • 97 citations

Biochemical aspects of telomerase function

2003 • 97 citations

Cooperation between p53 Mutation and High Telomerase Transgenic Expression in Spontaneous Cancer Development

2002 • 94 citations

Does the reservoir for self-renewal stem from the ends?

2004 • 65 citations

Telomeres in cancer and aging: lessons from the mouse

2003 • 35 citations

Telomere dysfunction results in enhanced organismal sensitivity to the alkylating agent N-methyl-N-nitrosourea.

2003 • 23 citations