Alterations in the Physical and Enzymic Properties of α-Chymotrypsin in Urea and Guanidinium Chloride^*

Optical Rotation And The Conformation Of Polypeptides And Proteins

1962 • 449 citations

The Optical Rotatory Dispersion of Polypeptides and Proteins in Relation to Configuration¹

1957 • 414 citations

Structural Studies of Ribonuclease. V. Reversible Change of Configuration^1-3

1961 • 263 citations

Studies on the Ultraviolet Difference Spectra of Proteins and Polypeptides

1961 • 205 citations

The Relationship of Structure to the Effectiveness of Denaturing Agents for Proteins

1963 • 203 citations

ACYLATION OF THE ENZYMATIC SITE OF δ-CHYMOTRYPSIN BY ESTERS, ACID ANHYDRIDES, AND ACID CHLORIDES

1957 • 155 citations

Ultraviolet Difference Spectra of Tyrosine Groups in Proteins and Amino Acids

1958 • 115 citations

Ultraviolet absorption spectra of poly-L-glutamic acid

1959 • 105 citations

Structural changes in the activation of chymotrypsinogen and trypsinogen. Effect of urea on chymotrypsinogen and delta-chymotrypsin

1956 • 103 citations

Tyrosyl-carboxylate ion hydrogen bonding in ribonuclease

1957 • 100 citations

Ultraviolet spectral changes related to the enzymic activity of chymotrypsin

1959 • 82 citations

Differential ultraviolet spectra of insulin

1956 • 81 citations

Reversible Denaturation of Pancreatic Ribonuclease by Urea

1962 • 68 citations

Tyrosyl Hydrogen Bonds in Insulin^1,2

1960 • 67 citations

Structural Studies of Ribonuclease. XI. Kinetics of Denaturation

1963 • 63 citations

Hydrophobic bonding and conformational transitions in lysozyme, ribonuclease and chymotrypsin

1961 • 62 citations

Ultraviolet Difference Spectra and the Internal Structure of Proteins

1960 • 55 citations

Structural transitions of lysozyme

1964 • 47 citations

Influence of ionization of carboxyl groups on the ultraviolet absorption spectrum of lysozyme

1958 • 34 citations

Evidence for Conformational Changes in α-Chymotrypsin Catalyzed Reactions. VII. Thermal Induced Reversible Changes of Conformation at pH 2.0

1963 • 32 citations

Effect of Solvent on the Optical Rotatory Dispersion of Uncharged Molecules Containing the Peptide Group

1962 • 31 citations

The Urea Denaturation of Chymotrypsinogen as Determined by Ultraviolet Spectral Changes. The Influence of pH and Salts¹

1960 • 31 citations

Spectrophotometric Titrations of Human Serum Albumin and Reduced Carboxymethylated Albumin

1963 • 29 citations

Characterization of the difference spectrum of diisopropylphosphoryl-α-chymotrypsin versus α-chymotrypsin IV. The environment of tryptophyl residues

1963 • 26 citations

The Urea Denaturation of α-Chymotrypsin

1963 • 21 citations

Changes in the ultraviolet absorption spectrum of trypsin associated with disruption of tertiary structure

1959 • 11 citations

The Urea Denaturation of α-Chymotrypsin in the Presence of Calcium

1963 • 6 citations

The urea inactivation of α-chymotrypsin: alterations in enzymic and physical properties

1961 • 4 citations

Synchrony in rates of absorbancy change upon denaturation of ovalbumin in urea

1964 • 3 citations