Interaction of a series of draflazine analogues with equilibrative nucleoside transporters: species differences and transporter subtype selectivity

The preparation and chemical characteristics of hemoglobin-free ghosts of human erythrocytes

1963 • 4,433 citations

Nucleoside and nucleobase transport systems of mammalian cells

1996 • 496 citations

Cloning of a human nucleoside transporter implicated in the Cellular uptake of adenosine and chemotherapeutic drugs

1997 • 426 citations

Nucleoside transporters: molecular biology and implications for therapeutic development

1999 • 349 citations

Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta

1997 • 278 citations

Molecular Cloning and Functional Characterization of Nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) Equilibrative Nucleoside Transporter Proteins (rENT1 and rENT2) from Rat Tissues

1997 • 227 citations

Cloning of the Human Equilibrative, Nitrobenzylmercaptopurine Riboside (NBMPR)-insensitive Nucleoside Transporter ei by Functional Expression in a Transport-deficient Cell Line

1998 • 225 citations

Recent advances in the molecular biology of nucleoside transporters of mammalian cells

1998 • 175 citations

Nucleoside transport and its significance for anticancer drug resistance

1998 • 154 citations

Chimeric Constructs between Human and Rat Equilibrative Nucleoside Transporters (hENT1 and rENT1) Reveal hENT1 Structural Domains Interacting with Coronary Vasoactive Drugs

1998 • 117 citations

Inhibitors of nucleoside transport. Structure-activity study using human erythrocytes

1975 • 114 citations

Erythrocyte nucleoside transport: asymmetrical binding of nitrobenzylthioinosine to nucleoside permeation sites

1982 • 102 citations

Nitrobenzylthioinosine-sensitive nucleoside transport system: mechanism of inhibition by dipyridamole.

1986 • 71 citations

BIBW 22, a dipyridamole analogue, acts as a bifunctional modulator on tumor cells by influencing both P-glycoprotein and nucleoside transport.

1993 • 55 citations

Nucleoside Transport Inhibitors: Structure-Activity Relationships and Potential Therapeutic Applications

1997 • 54 citations

Inhibition of adenosine uptake in human erythrocytes by adenosine-5'-carboxamides, xylosyladenine, dipyridamole, hexobendine, and p-nitrobenzylthioguanosine

1978 • 52 citations

Comparative Pharmacology of Nucleoside Transport Inhibitors

1991 • 49 citations

Species differences in sensitivity of nucleoside transport in erythrocytes and cultured cells to inhibition by nitrobenzylthioinosine, dipyridamole, dilazep and lidoflazine

1988 • 48 citations

Hemodynamic and neurohumoral effects of various grades of selective adenosine transport inhibition in humans. Implications for its future role in cardioprotection.

1995 • 48 citations

[3H]Nitrobenzylthioinosine Binding to the Guinea Pig CNS Nucleoside Transport System: A Pharmacological Characterization

1984 • 44 citations

Enzymic cleavage as a probe of the molecular structures of mammalian equilibrative nucleoside transporters.

1993 • 38 citations

Inhibition of nucleoside transport by a new series of compounds related to lidoflazine and mioflazine

1989 • 37 citations

Comparative pharmacology of the nitrobenzylthioguanosine-sensitive and -resistant nucleoside transport mechanisms of Ehrlich ascites tumor cells.

1991 • 36 citations

Inhibition of uridine uptake in HeLa cells by nitrobenzylthioinosine and related compounds.

1977 • 32 citations

Kinetic analysis of ligand binding to the Ehrlich cell nucleoside transporter: pharmacological characterization of allosteric interactions with the [3H]nitrobenzylthioinosine binding site.

1991 • 32 citations

Adenosine Transport by Rat and Guinea Pig Synaptosomes: Basis for Differential Sensitivity to Transport Inhibitors

1990 • 30 citations

Benzodiazepine inhibition of nucleoside transport in human erythrocytes

1983 • 30 citations

External location of sites on pig erythrocyte membranes that bind nitrobenzylthioinosine.

1988 • 28 citations

Mapping the binding site of the nucleoside transporter protein: a 3D-QSAR study

1990 • 23 citations

Solubilization and reconstitution of a nucleoside-transport system from Ehrlich ascites-tumour cells

1989 • 22 citations

Differential inhibition of nucleoside transport systems in mammalian cells by a new series of compounds related to lidoflazine and mioflazine

1990 • 18 citations

Nucleoside transport inhibition and platelet aggregation in human blood: R75231 and its enantiomers, draflazine and R88016

1994 • 18 citations

Potencies of mioflazine and its derivatives as inhibitors of adenosine transport in isolated erythrocytes from different species

1990 • 15 citations

Studies of the nucleoside transporter inhibitor, draflazine, in the human myocardium

1994 • 15 citations

Competition of nucleoside transport inhibitors with binding of 6-[(4-nitrobenzyl)-mercapto]purine ribonucleoside to intact erythrocytes and ghost membranes from different species

1990 • 11 citations

Inhibition of nucleoside uptake in human erythrocytes by a new series of compounds related to lidoflazine and mioflazine

1990 • 10 citations

[3H]R75231 — a new radioligand for the nitrobenzylthioinosine sensitive nucleoside transport proteins Characterization of (±)-[3H]R75231 binding to calf lung membranes, stereospecificity of its two stereoisomers, and comparison with [3H]nitrobenzylthioinosine binding

1992 • 9 citations

Inhibition of nucleoside transport by nitrobenzylthioformycin analogs

1990 • 8 citations

Effects of chemical modification of nitrobenzylthioinosine on its binding to high-affinity membrane binding sites and inhibition of nucleoside transport

1992 • 6 citations

Interaction of the mioflazine derivative R75231 with the nucleoside transporter: evidence for positive cooperativity

1993 • 6 citations

Myocardial protection by nucleoside transport inhibition.

1995 • 6 citations