Increased calcium sensitivity of chemically skinned human atria by myosin light chain kinase

Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells.

1979 • 1,648 citations

The direct linear plot. A new graphical procedure for estimating enzyme kinetic parameters

1974 • 1,571 citations

Okadaic acid, a cytotoxic polyether from two marine sponges of the genus Halichondria

1981 • 742 citations

An electrophoretic study of the low-molecular-weight components of myosin

1970 • 706 citations

[41] Assay of cyclic AMP-dependent protein kinases

1974 • 498 citations

Smooth muscle myosin phosphatase inhibition and force enhancement by black sponge toxin

1987 • 280 citations

The effect of myosin phosphorylation on the contractile properties of skinned rabbit skeletal muscle fibers.

1985 • 246 citations

Effect of rigor and cycling cross-bridges on the structure of troponin C and on the Ca2+ affinity of the Ca2+-specific regulatory sites in skinned rabbit psoas fibers.

1987 • 227 citations

Phosphorylation of myosin in permeabilized mammalian cardiac and skeletal muscle cells

1986 • 170 citations

Phosphorylation of the light-chain components of myosin from cardiac and red skeletal muscles

1975 • 163 citations

Myosin types in the human heart. An immunofluorescence study of normal and hypertrophied atrial and ventricular myocardium.

1984 • 161 citations

Purification and characterization of bovine cardiac calmodulin-dependent myosin light chain kinase.

1979 • 153 citations

Purification of myosin light chain kinase from bovine cardiac muscle.

1980 • 109 citations

The influence of P‐light chain phosphorylation by myosin light chain kinase on the calcium sensitivity of chemically skinned heart fibres

1985 • 97 citations

Phosphorylation of the 19,000-dalton light chain of myosin in perfused rat heart under the influence of negative and positive inotropic agents.

1979 • 95 citations

The cross-bridge cycle in muscle. Mechanical, biochemical, and structural studies on single skinned rabbit psoas fibers to characterize cross-bridge kinetics in muscle for correlation with the actomyosin-ATPase in solution

1986 • 83 citations

Skinned fibers of human atrium and ventricle: myosin isoenzymes and contractility.

1988 • 78 citations

The effect of adrenaline on the phosphorylation of the P light chain of myosin and troponin I in the perfused rabbit heart

1981 • 77 citations

Molecular Mechanism of Muscle Contraction

1987 • 74 citations

Isolation of cardiac myofibrils and myosin light chains with in vivo levels of light chain phosphorylation

1979 • 74 citations

Phosphorylation of myosin in perfused rabbit and rat hearts

1980 • 60 citations

Frequency-dependent myosin light chain phosphorylation in isolated myocardium

1986 • 54 citations

Phosphorylation of myosin light chains in perfused rat heart. Effect of adrenaline and increased cytoplasmic calcium ions

1980 • 50 citations

Increased cardiac myosin ATPase activity as a biochemical adaptation to running training: Enhanced response to catecholamines and a role for myosin phosphorylation

1981 • 42 citations

Myosin isoenzymes in human hypertrophic hearts. Shift in atrial myosin heavy chains and in ventricular myosin light chains

1984 • 41 citations

Electromechanical effects of okadaic acid isolated from black sponge in guinea‐pig ventricular muscles.

1986 • 36 citations

Myosin isoenzymes of vascular smooth and cardiac muscle in the spontaneously hypertensive and normotensive male and female rat: a comparative study.

1986 • 36 citations

Modulation of Aortic Protein Phosphatase Activity by Polylysine

1984 • 24 citations

Further studies on the effects of myosin P-light chain phosphorylation on contractile properties of skinned cardiac fibres

1986 • 23 citations

Phosphorylation of myosin light chains in perfused rat heart

1980 • 18 citations

Calcium sensitivity of myofilaments in cardiac muscle — effect of myosin phosphorylation

1986 • 16 citations

Altered adenosine triphosphatase activities of natural actomyosin from rat hearts perfused with isoprenaline and ouabain

1981 • 15 citations

Myosin light chain phosphorylation during contraction of turtle heart

1983 • 12 citations

Myofibrillar calcium sensitivity modulation: influence of light chain phosphorylation and positive inotropic drugs on skinned frog skeletal muscle.

1988 • 8 citations

Unchanged myosin kinase activity in hypertrophied rat heart

1984 • 1 citations