Convection-enhanced distribution of large molecules in gray matter during interstitial drug infusion

New Methods of Drug Delivery

1990 • 1,730 citations

Trophic factors and neuronal survival

1989 • 1,631 citations

Convection-enhanced delivery of macromolecules in the brain.

1994 • 1,357 citations

An anterograde neuroanatomical tracing method that shows the detailed morphology of neurons, their axons and terminals: Immunohistochemical localization of an axonally transported plant lectin,Phaseolus vulgaris leucoagglutinin (PHA-L)

1984 • 1,205 citations

Polymers for the sustained release of proteins and other macromolecules

1976 • 1,127 citations

The changing scene of neurotrophic factors

1991 • 827 citations

Intrathecal chemotherapy: brain tissue profiles after ventriculocisternal perfusion.

1975 • 321 citations

High-flow microinfusion: tissue penetration and pharmacodynamics

1994 • 311 citations

Efflux of radiolabeled polyethylene glycols and albumin from rat brain

1981 • 311 citations

In vivo anterograde and retrograde axonal trnasport of the fluoresecent rhodamine-dextran-amine, Fluor-Ruby, within the CNS

1990 • 241 citations

Flow of cerebral interstitial fluid as indicated by the removal of extracellular markers from rat caudate nucleus

1977 • 227 citations

Bulk flow of brain interstitial fluid under normal and hyperosmolar conditions

1980 • 205 citations

Intracranial chemical injection and behavior: A critical review

1972 • 198 citations

Drugs released from polymers: diffusion and elimination in brain tissue

1991 • 170 citations

Blood-Brain Barrier: Interface Between Internal Medicine and the Brain

1986 • 160 citations

Drug “Diffusion” within the Brain^a

1988 • 134 citations

Osmotic Opening of the Blood-Brain Barrier in the Monkey without Associated Neurological Deficits

1973 • 116 citations

Textbook of Neuropathology

1991 • 90 citations

Transport of material between brain extracellular fluid, brain cells and blood.

1974 • 80 citations

Clearance of brain edema and macromolecules through the cortical extracellular space

1992 • 78 citations

Intracerebral Chemotherapy

1982 • 78 citations

Spatial distribution of dopamine, methotrexate and antipyrine during continuous intracerebral microperfusion

1985 • 72 citations

Transport of Cisplatin in Rat Brain Following Microinfusion: an Analysis

1986 • 59 citations

Experimental peritumoral edema of the cat brain.

1980 • 39 citations

Drug distribution in solid tissue of the brain following chronic local perfusion utilizing implanted osmotic minipumps

1984 • 24 citations

Dopamine distribution and behavioral alterations resulting from dopamine infusion into the brain of the lesioned rat

1991 • 19 citations

New “micro push-pull” catheter system for localized perfusion of diminutive structures in brain

1985 • 16 citations

New marker for nerve damage

1993 • 9 citations

The Kinetics of Fluid Movement through Brain Tissue

1984 • 8 citations