Production of hydroxyectoine: high cell-density cultivation and osmotic downshock of Marinococcus strain M52

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

Measurement of protein using bicinchoninic acid

1985 • 17,516 citations

Microbial water stress

1976 • 742 citations

Enzyme stabilization be ectoine-type compatible solutes: protection against heating, freezing and drying

1992 • 409 citations

1,4,5,6-Tetrahydro-2-methyl-4-pyrimidinecarboxylic acid. A novel cyclic amino acid from halophilic phototrophic bacteria of the genus Ectothiorhodospira

1985 • 399 citations

Compatible solutes of halophilic eubacteria: molecular principles, water-solute interaction, stress protection

1993 • 322 citations

Generalization of monod kinetics for analysis of growth data with substrate inhibition

1987 • 297 citations

Betaine, a compatible solute in the extremely halophilic phototrophic bacteriumEctothiorhodospira halochloris

1982 • 185 citations

The predominant role of recently discovered tetrahydropyrimidines for the osmoadaptation of halophilic eubacteria

1992 • 185 citations

The predominant role of recently discovered tetrahydropyrimidines for the osmoadaptation of halophilic eubacteria

1992 • 165 citations

The spectrum of compatible solutes in heterotrophic halophilic eubacteria of the family Halomonadaceae

1990 • 155 citations

An osmoregulated dipeptide in stressed Rhizobium meliloti

1989 • 118 citations

Transient, specific and extremely rapid release of osmolytes from growing cells of Escherichia coli K-12 exposed to hypoosmotic shock

1993 • 113 citations

Sporosarcina halophila sp. nov., an Obligate, Slightly Halophilic Bacterium from Salt Marsh Soils

1983 • 111 citations

Survival of Escherichia coli during drying and storage in the presence of compatible solutes

1994 • 104 citations

Recombinant trypsin production in high cell density fed‐batch cultures in Escherichia coli

1993 • 96 citations

Regulation of compatible solute accumulation in Salmonella typhimurium: evidence for a glycine betaine efflux system

1991 • 95 citations

A modified FMOC-method for the detection of amino acid-type osmolytes and tetrahydropyrimidines (ectoines)

1993 • 89 citations

Fed‐batch operation of recombinant Escherichia coli containing trp promoter with controlled specific growth rate

1994 • 77 citations

Transient breakdown of the permeability barrier of the membrane of Escherichia coli upon hypoosmotic shock

1977 • 76 citations

Compatible solutes in representatives of the generaBrevibacteriumandCorynebacterium: Occurrence of tetrahydropyrimidines and glutamine

1993 • 66 citations

Cultivation of Escherichia coli to high cell densities in a dialysis reactor

1993 • 64 citations

A predictive and feedback control algorithm maintains a constant glucose concentration in fed-batch fermentations

1991 • 62 citations

Fate of compatible solutes during dilution stress inEctothiorhodospira halochloris

1990 • 40 citations

Compatible solutes in new moderately halophilic isolates

1994 • 33 citations

Identification of N ?-acetylornithine as a novel osmolyte in some Gram-positive halophilic eubacteria

1993 • 25 citations

A modified method of quantitative colorimetric DNA-DNA hybridization on membrane filters for bacterial identification

1994 • 21 citations

Intracellular salt and solute concentrations in Ectothiorhodospira marismortui: glycine betaine and N?-carbamoyl glutamineamide as osmotic solutes

1991 • 19 citations

Development of high-cell-density fermentation for heterologous interleukin 1\ production in Kluyveromyces lactis controlled by the PH05 promoter

1994 • 17 citations