Aspartic acid aminotransferase activity is increased in actively spiking compared with non-spiking human epileptic cortex.

UPTAKE AND METABOLISM OF GLUTAMATE IN ASTROCYTES CULTURED FROM DISSOCIATED MOUSE BRAIN HEMISPHERES

1977 • 343 citations

Metabolic Fate of ¹⁴C‐Labeled Glutamate in Astrocytes in Primary Cultures

1982 • 287 citations

“Epileptic” brain damage is replicated qualitatively in the rat hippocampus by central injection of glutamate or aspartate but not by GABA or acetylcholine

1985 • 242 citations

A selective N-methyl-d-aspartate antagonist depresses epileptiform activity in rat hippocampal slices

1985 • 205 citations

Antiepileptic action of excitatory amino acid antagonists in the photosensitive baboon, papio papio

1983 • 179 citations

Rapid measurement of free amino acids in serum and CSF using high-performance liquid chromatography

1981 • 134 citations

Amino Acids in the Cobalt-Induced Epileptogenic and Nonepileptogenic Cat's Cortex

1972 • 129 citations

Excitatory amino acids are elevated in human epileptic cerebral cortex

1988 • 128 citations

Close correlation between changing content of specific amino acids in epileptogenic cortex of cats, and severity of epilepsy

1972 • 126 citations

Bursting in human epileptogenic neocortex is depressed by an antagonist

1987 • 116 citations

Role of excitatory amino acid transmission in the genesis of seizures elicited from the deep prepiriform cortex

1986 • 111 citations

Effect of n‐dipropylacetate on amino acid concentrations in mouse brain: correlations with anti‐convulsant activity

1978 • 108 citations

FREE AMINO ACID LEVELS IN THE CEREBROSPINAL FLUID OF NORMAL HUMANS AND THEIR VARIATION IN CASES OF EPILEPSY AND SPIELMEYER‐VOGT‐BATTEN DISEASE

1974 • 85 citations

Soft sheets of fibrillar bone from a fossil of the supraorbital horn of the dinosaur Triceratops horridus

2013 • 84 citations

Neurochemical and morphological changes during the development of cobalt-induced epilepsy in the rat

1975 • 84 citations

Acute anticonvulsant activity of structural analogues of valproic acid and changes in brain GABA and aspartate content

1983 • 75 citations

Putative amino acid transmitters in lumbar cerebrospinal fluid of patients with histologically verified Alzheimer's dementia.

1985 • 73 citations

Brain regional amino acid levels in seizure susceptible rats: Changes related to sound-induced seizures

1986 • 70 citations

Enzyme changes in actively spiking areas of human epileptic cerebral cortex

1984 • 69 citations

Changes in Regional Neurotransmitter Amino Acid Levels in Rat Brain During Seizures Induced by <scp>l</scp>‐Allylglycine, Bicuculline, and Kainic Acid

1984 • 62 citations

Suppression of audiogenic seizures in DBA/2 mice by two new dipeptide NMDA receptor antagonists

1984 • 57 citations

Activity of Acetylcholine System in Human Epileptogenic Focus

1952 • 52 citations

Differential Changes in the Content of Amino Acid Neurotransmitters in Discrete Regions of the Rat Brain Prior to the Onset and During the Course of Homocysteine‐Induced Seizures

1986 • 52 citations

Changes in cortical amino acids during electrical kindling in rats

1985 • 42 citations

Cerebral free amino acids in the amygdaloid kindling model of epilepsy

1982 • 37 citations

Effects of Two Convulsant β‐Carboline Derivatives, DMCM and β‐CCM, on Regional Neurotransmitter Amino Acid Levels and on In Vitro D‐[³H]Aspartate Release in Rodents

1985 • 35 citations

Alterations in the Content of Amino Acid Neurotransmitters Before the Onset and During the Course of Methoxypyridoxine‐Induced Seizures in Individual Rabbit Brain Regions

1983 • 30 citations

Increased concentrations of aspartic acid in the cerebrospinal fluid of patients with epilepsy and trigeminal neuralgia: an effect of medication?

2009 • 24 citations

Aspects of the pentylenetetrazol kindling model of epileptogenesis in the rat

1982 • 22 citations

Alteration of Amino Acid Metabolism in Epileptogenic Mice by Elevation of Brain Pyridoxal Phosphate

1985 • 22 citations

Reduced Cortical Glutamine Concentrations in Electrically Kindled Rats

1983 • 15 citations

Excitatory Amino Acid Antagonists as Novel Anticonvulsants

1986 • 15 citations

METABOLIC INVESTIGATIONS OF EPILEPTIC SEIZURES

1969 • 11 citations

A Possible Role for Aspartic Acid in Neonatal Seizures

1981 • 10 citations

[11] Glutamate-aspartate transaminase

1985 • 8 citations

Effect of α‐Amino‐4‐Phosphonobutyrate on the Release of Endogenous Glutamate and Aspartate from Cortical Synaptosomes of Epileptic Rats

1985 • 6 citations