Insulin Inhibits Intranuclear Nuclear Factor κB and Stimulates IκB in Mononuclear Cells in Obese Subjects: Evidence for an Anti-inflammatory Effect?

Atherosclerosis — An Inflammatory Disease

1999 • 21,494 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

1997 • 4,661 citations

Elevated C-Reactive Protein Levels in Overweight and Obese Adults

1999 • 2,384 citations

A rapid micrqpreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

1991 • 2,362 citations

Inhibition of NF-κB by Sodium Salicylate and Aspirin

1994 • 1,743 citations

IMF-κB and Rel: Participants in a Multiform Transcriptional Regulatory System

1993 • 967 citations

Glycometabolic State at Admission: Important Risk Marker of Mortality in Conventionally Treated Patients With Diabetes Mellitus and Acute Myocardial Infarction

1999 • 873 citations

Oxidative damage to DNA in diabetes mellitus

1996 • 789 citations

Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells.

1996 • 735 citations

Inflammation, free radicals, and antioxidants

1996 • 694 citations

Glucose Challenge Stimulates Reactive Oxygen Species (ROS) Generation by Leucocytes

2000 • 598 citations

Regulation of the NF-ηB/rel transcription factor and IηB inhibitor system

1993 • 541 citations

The Suppressive Effect of Dietary Restriction and Weight Loss in the Obese on the Generation of Reactive Oxygen Species by Leukocytes, Lipid Peroxidation, and Protein Carbonylation1

2001 • 366 citations

Review: Oxidative Stress and Disease

2000 • 230 citations

Incidence of cardiovascular disease in Type 1 (insulin-dependent) diabetic subjects with and without diabetic nephropathy in Finland

1998 • 224 citations

The inhibition by diphenyleneiodonium and its analogues of superoxide generation by macrophages

1987 • 211 citations

The Respiratory Burst Oxidase

1992 • 198 citations

Insulin Inhibits the Expression of Intercellular Adhesion Molecule-1 by Human Aortic Endothelial Cells through Stimulation of Nitric Oxide1

2000 • 167 citations

Effect of insulin on human aortic endothelial nitric oxide synthase

2000 • 148 citations

Mechanisms of monocyte recruitment and accumulation

1993 • 147 citations

Insulin-mediated vasodilation: impairment with increased blood pressure and body mass

1993 • 144 citations

Reduction of hospital mortality rate of acute myocardial infarction with glucose-insulin-potassium infusion

1976 • 143 citations

Troglitazone Reduces Reactive Oxygen Species Generation by Leukocytes and Lipid Peroxidation and Improves Flow-Mediated Vasodilatation in Obese Subjects

2000 • 143 citations

Insulin resistance and insulin deficiency in the pathogenesis of Type 2 (non-insulin-dependent) diabetes mellitus: errors of metabolism or of methods?

1993 • 140 citations

Insulin Therapy Improves Endothelial Function in Type 2 Diabetes

2000 • 123 citations

The Mystery of Diabetes and Atherosclerosis: Time for a New Plot

1997 • 117 citations

Insulin as a mitogenic factor: Role in the pathogenesis of cardiovascular disease

1991 • 104 citations

NITRIC OXIDE ATTENUATES ADHESION MOLECULE EXPRESSION IN HUMAN ENDOTHELIAL CELLS

1996 • 97 citations

Insulin Attenuates Norepinephrine- Induced Venoconstriction

1995 • 84 citations

Oxygen Free Radicals in Tissue Damage

1993 • 80 citations

Atherosclerosis as an Inflammatory Process

1985 • 60 citations

A Rapid, Specific assay for Superoxide Release from Phagocytes in Small Volumes of Whole Blood

1992 • 57 citations

Effect of hydrocortisone on oxygen free radical generation by mononuclear cells

1998 • 55 citations

Increased IκB Expression and Diminished Nuclear NF-κB in Human Mononuclear Cells following Hydrocortisone Injection

1999 • 49 citations

Biochemistry of the Arterial Wall in Developing Atherosclerosisa

1991 • 32 citations

Monocytes/macrophages in atherosclerosis.

1998 • 30 citations

Inhaled NO reduces leukocyte-endothelial cell interactions and myocardial dysfunction in endotoxemic rats

2000 • 30 citations

Cellular mechanisms in the development of atherosclerosis

1996 • 30 citations

Intensive Insulin Therapy in Type II Diabetes: Rationale and Collaborative Clinical Trial Results

1996 • 28 citations

Insulin and atherogenesis

1992 • 28 citations

Acute suppressive effect of hydrocortisone on p47phox subunit of nicotinamide adenine dinucleotide phosphate oxidase

2001 • 22 citations

Free-radical generation by monocytes and neutrophils: a possible cause of plasma lipoprotein modification.

1991 • 13 citations

Diacylglycerols modulate phosphorylation of the insulin receptor from human mononuclear cells

1990 • 11 citations

Cardiovascular disease in diabetes and operative risk.

1998 • 6 citations