Genetic polymorphism in drug oxidation: In vitro studies of human debrisoquine 4-hydroxylase and bufuralol 1′-hydroxylase activities

POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN

1977 • 1,196 citations

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

1980 • 544 citations

Defective Oxidation of Drugs

1982 • 182 citations

Biological oxidation of nitrogen

1979 • 158 citations

Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.

1980 • 152 citations

Evidence for an enzymatic defect in the 4‐hydroxylation of debrisoquine by human liver.

1981 • 93 citations

The genetic controlof bufuralol metabolisminman

1982 • 76 citations

Assay and characterisation of debrisoquine 4‐hydroxylase activity of microsomal fractions of human liver.

1982 • 64 citations

In vitro metabolism of sparteine by human liver: competitive inhibition by debrisoquine

1982 • 38 citations