T cells as antigen-presenting cells

Antigen-specific interaction between T and B cells

1985 • 1,396 citations

The Role of the CD28 Receptor During T Cell Responses to Antigen

1993 • 1,320 citations

A new member of the immunoglobulin superfamily—CTLA-4

1987 • 1,214 citations

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

1991 • 1,132 citations

Activation-induced death by apoptosis in CD4+ T cells from human immunodeficiency virus-infected asymptomatic individuals.

1992 • 907 citations

Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis

1989 • 588 citations

Vaccination against autoimmune encephalomyelitis with T-lymphocite line cells reactive against myelin basic protein

1981 • 520 citations

Anti-Idiotypic Network Induced by T Cell Vaccination Against Experimental Autoimmune Encephalomyelitis

1988 • 409 citations

Human TH1 and TH2 Subsets: Regulation of Differentiation and Role in Protection and Immunopathology

1992 • 383 citations

Peripheral human T cells sensitized in mixed leukocyte culture synthesize and express Ia-like antigens.

1978 • 374 citations

Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: Effect of HIV sequence variation and a mechanism for CD4+ cell depletion

1988 • 372 citations

Peripheral blood Ia-positive T cells. Increases in certain diseases and after immunization.

1980 • 333 citations

Suppression of experimentally induced autoimmune encephalomyelitis by cytolytic T–T cell interactions

1988 • 324 citations

B lymphoblast antigen (BB-1) expressed on Epstein-Barr virus-activated B cell blasts, B lymphoblastoid cell lines, and Burkitt's lymphomas.

1982 • 297 citations

T cells can present antigens such as HIV gp120 targeted to their own surface molecules

1988 • 294 citations

MHC-Restricted Depletion of Human Myelin Basic Protein-Reactive T Cells by T Cell Vaccination

1993 • 286 citations

The B7/BB1 antigen provides one of several costimulatory signals for the activation of CD4+ T lymphocytes by human blood dendritic cells in vitro.

1992 • 273 citations

Functional expression of B7/BB1 on activated T lymphocytes.

1993 • 271 citations

B7, a B-cell-restricted antigen that identifies preactivated B cells.

1987 • 211 citations

Early signaling defects in human T cells anergized by T cell presentation of autoantigen.

1992 • 143 citations

A human suppressor T cell clone which recognizes an autologous helper T cell clone

1982 • 119 citations

B7/BB1, the ligand for CD28, is expressed on repeatedly activated human T cells in vitro

1993 • 117 citations

Professional presentation of antigen by activated human T cells

1994 • 112 citations

Transferrin receptor mediates uptake and presentation of hepatitis B envelope antigen by T lymphocytes.

1992 • 98 citations

Specific killing of cytotoxic T cells and antigen-presenting cells by CD4+ cytotoxic T cell clones. A novel potentially immunoregulatory T-T cell interaction in man.

1990 • 95 citations

Clonal analysis of differential lymphokine production in peptide and superantigen induced T cell anergy

1991 • 95 citations

Comparative clonal analysis of human immunodeficiency virus type 1 (HIV-1)-specific CD4+ and CD8+ cytolytic T lymphocytes isolated from seronegative humans immunized with candidate HIV-1 vaccines.

1992 • 94 citations

The B7 adhesion molecule is expressed on activated human T cells: Functional involvement in T‐T cell interactions

1993 • 85 citations

Presentation of autoantigen by human T cells.

1991 • 80 citations

Antigen processing and CD4+ T cell depletion in AIDS

1988 • 65 citations

Human T cell clones present antigen.

1989 • 53 citations

Human T cell autoimmunity against myelin basic protein: CD4⁺ cells recognizing epitopes of the T cell receptor β chain from a myelin basic protein‐specific T cell clone

1993 • 49 citations

Antigen‐presenting human T cells and antigen‐presenting B cells induce a similar cytokine profile in specific T cell clones

1993 • 36 citations

Is suppression a function of class II- restricted cytotoxic T cells?

1989 • 35 citations

Protection against experimental encephalomyelitis: Idiotypic autoregulation induced by a non-encephalitogenic T cell clone expressing a cross-reactive T cell receptor V gene

1992 • 31 citations

Discrimination of human CD4 T cell clones based on their reactivity with antigen‐presenting T cells

1992 • 28 citations

Protection against experimental encephalomyelitis. Idiotypic autoregulation induced by a nonencephalitogenic T cell clone expressing a cross-reactive T cell receptor V gene.

1991 • 27 citations

Use of antibody/peptide constructs to direct antigenic peptides to T cells: Evidence for T cell processing and presentation

1992 • 20 citations