Efficiency of antigen presentation to T cell clones by (B cell × B cell lymphoma) hybridomas correlates quantitatively with cell surface Ia antigen expression

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

Lymphoid dendritic cells are potent stimulators of the primary mixed leukocyte reaction in mice.

1978 • 791 citations

Establishment and Characterization of BALB/c Lymphoma Lines with B Cell Properties

1979 • 677 citations

The Regulatory Role of Macrophages in Antigenic Stimulation Part Two: Symbiotic Relationship between Lymphocytes and Macrophages

1981 • 518 citations

Antigen presentation: comments on its regulation and mechanism.

1984 • 498 citations

A hypothesis to relate the specificity of T lymphocytes and the activity of I region-specific Ir genes in macrophages and B lymphocytes.

1978 • 488 citations

MONOCLONAL ANTIBODIES TO MOUSE MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGENS

1982 • 471 citations

Determinant Selection and Macrophage Function in Genetic Control of the Immune Response

1978 • 389 citations

Studies on the capacity of B cells to serve as antigen-presenting cells.

1981 • 349 citations

The traditional and a new version of the mouse H–2 complex

1981 • 325 citations

Magnitude of response of histocompatibility-restricted T-cell clones is a function of the product of the concentrations of antigen and Ia molecules.

1983 • 312 citations

A rat anti-mouse T4 monoclonal antibody (H129.19) inhibits the proliferation of Ia-reactive T cell clones and delineates two phenotypically distinct (T4+, Lyt-2,3-, and T4-, Lyt-2,3+) subsets among anti-Ia cytolytic T cell clones.

1984 • 308 citations

Opinion

1978 • 283 citations

Antigen presentation by Ia+ B cell hybridomas to H-2-restricted T cell hybridomas.

1982 • 252 citations

Inhibition of murine T cell‐mediated cytolysis and T cell proliferation by a rat monoclonal antibody immunoprecipitating two lymphoid cell surface polypeptides of 94000 and 180000 molecular weight

1982 • 237 citations

Clonal analysis of B- and T-cell responses to Ia antigens

1981 • 205 citations

Ia antigen-bearing B cell tumor lines can present protein antigen and alloantigen in a major histocompatibility complex-restricted fashion to antigen-reactive T cells.

1982 • 202 citations

Expression of Ia antigens by cultured astrocytes treated with gamma-interferon

1983 • 182 citations

A Clonal Deletion Model for Ir Gene Control of the Immune Response

1978 • 156 citations

Major histocompatibility complex-restricted antigen presentation to antigen-reactive T cells by B lymphocyte tumor cells.

1981 • 153 citations

Gene transfer of H-2 class II genes: Antigen presentation by mouse fibroblast and hamster B-cell lines

1984 • 135 citations

Rat monoclonal antibodies. I. Rapid purification from in vitro culture supernatants

1984 • 119 citations

Immune response gene function correlates with the expression of an Ia antigen. II. A quantitative deficiency in A(e):E(a), complex expression causes a corresponding defect in antigen-presenting cell function

1982 • 115 citations

Characterization of the gamma-interferon-mediated induction of antigen-presenting ability in P388D1 cells.

1983 • 101 citations

Distinct epitopes on I^k gene products identified by monoclonal antibodies

1980 • 101 citations

IA mutant functional antigen-presenting cell lines.

1983 • 100 citations

Antigen-specific. I region-restricted interactions in vitro between tumor cell lines and T cell hybridomas.

1982 • 96 citations

Quantification by flow cytofluorimetry of HLA class I molecules at the surface of murine cells transformed by cloned HLA genes

1983 • 84 citations

Quantitative immunofluorescent analysis of surface phenotypes of murine B cell lymphomas and plasmacytomas with monoclonal antibodies.

1981 • 81 citations

Establishment of B cell hybridomas with B cell surface antigens.

1982 • 80 citations

Secretion of mediators following T lymphocyte-macrophage interaction is regulated by the major histocompatibility complex.

1977 • 79 citations

I region-restricted antigen presentation by B cell–B lymphoma hybridomas

1982 • 74 citations

Concomitant induction of the cell surface expression of Ia determinants and accessory cell function by a murine macrophage tumor cell line.

1982 • 72 citations

Functional expression of a transfected murine class II MHC gene

1983 • 59 citations

Antigen presentation to T cell hybridomas by a macrophage cell line: an inducible function.

1982 • 45 citations

Serologic and functional characterization of a panel of antigen-presenting cell lines expressing mutant I-A class II molecules.

1983 • 42 citations

Dissection of the poly(Glu60 Ala30 Tyr10) (GAT)-specific T-cell repertoire in H-2I k mice

1983 • 35 citations

Dissection of the poly(glu60ala30tyr10) (GAT)-specific T-cell repertoire in H-21 k mice

1983 • 26 citations

In vitro correlate for a clonal deletion mechanism of immune response gene-controlled nonresponsiveness.

1983 • 23 citations

Murine H-2Dd-reactive monoclonal antibodies recognize shared antigenic determinant(s) on human HLA-B7 or HLA-B27 molecules or both

1983 • 21 citations

Fine specificity of a proliferating T-cell clone activated by a conformational determinant of the I-Ek molecule

1982 • 18 citations

Biochemical characterization of B lymphoma cell antigen processing and presentation to antigen-reactive T cells.

1983 • 17 citations

Clonal analysis of B and T cell responses to Ia antigens. IV. Proliferative T cell clones recognizing E beta and/or E alpha allodeterminants.

1983 • 15 citations

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