Angiotensin II antagonists for hypertension: are there differences in efficacy?

Treatment of Mild Hypertension Study. Final results. Treatment of Mild Hypertension Study Research Group

1993 • 841 citations

Valsartan

1997 • 314 citations

Continuation of initial antihypertensive medication after 1 year of therapy

1998 • 309 citations

Losartan Potassium

1996 • 249 citations

A Randomized, Placebo-Controlled, Double-Blind, Parallel Study of Various Doses of Losartan Potassium Compared With Enalapril Maleate in Patients With Essential Hypertension

1995 • 223 citations

Comparative Efficacy of Two Angiotensin II Receptor Antagonists, Irbesartan and Losartan, in Mild-to-Moderate Hypertension

1998 • 169 citations

The efficacy and safety of valsartan compared with placebo in the treatment of patients with essential hypertension

1996 • 152 citations

Losartan and Low-Dose Hydrochlorothiazide in Patients With Essential Hypertension

1996 • 140 citations

Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: A comparative study of the efficacy and safety against amlodipine*

1996 • 138 citations

The Antihypertensive Effect and Tolerability of Candesartan Cilexetil, a New Generation Angiotensin II Antagonist, in Comparison with Losartan

1998 • 136 citations

Irbesartan

1997 • 133 citations

Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared with placebo and enalapril

1996 • 127 citations

Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy, tolerability and safety compared to an angiotensin-converting enzyme inhibitor, lisinopril

1997 • 122 citations

Comparison of the angiotensin II antagonist losartan with the angiotensin converting enzyme inhibitor enalapril in patients with essential hypertension

1995 • 114 citations

Dose-Related Antihypertensive Effects of Irbesartan in Patients With Mild-to-Moderate Hypertension

1998 • 110 citations

Efficacy and tolerability of losartan potassium and atenolol in patients with mild to moderate essential hypertension*

1995 • 101 citations

Losartan, an orally active angiotensin (AT1) receptor antagonist: a review of its efficacy and safety in essential hypertension

1997 • 98 citations

An elective-titration study of the comparative effectiveness of two angiotensin II-receptor blockers, irbesartan and losartan

1998 • 94 citations

Dose-Related Efficacy of Irbesartan for Hypertension

1998 • 90 citations

A randomised, double-blind comparison of the angiotensin II receptor antagonist, irbesartan, with the full dose range of enalapril for the treatment of mild-to-moderate hypertension

1998 • 89 citations

Intent-to-Treat Analysis versus As-Treated Analysis

1996 • 87 citations

Effects and Tolerability of Irbesartan Versus Enalapril in Patients With Severe Hypertension fn1fn1This study was supported by a grant from Bristol-Myers Squibb, Princeton, New Jersey.

1997 • 86 citations

Efficacy, tolerability, and effects on quality of life of losartan, alone or with hydrochlorothiazide, versus amlodipine, alone or with hydrochlorothiazide, in patients with essential hypertension

1996 • 84 citations

Controlled Trial of Losartan Given Concomitantly with Different Doses of Hydrochlorothiazide in Hypertensive Patients

1996 • 76 citations

Candesartan cilexetil, a new generation angiotensin II antagonist, provides dose dependent antihypertensive effect.

1997 • 73 citations

Comparison of the Angiotensin II Receptor Antagonist Irbesartan With Atenolol for Treatment of Hypertension

1998 • 59 citations

24-Hour blood pressure control by once-daily administration of irbesartan assessed by ambulatory blood pressure monitoring

1997 • 59 citations

Efficacy and tolerability of losartan versus enalapril alone or in combination with hydrochlorothiazide in patients with essential hypertension

1995 • 58 citations

Effects of candesartan cilexetil in patients with severe systemic hypertension

1999 • 56 citations

Efficacy, tolerability, and quality of life of losartan, alone or with hydrochlorothiazide, versus nifedipine GITS in patients with essential hypertension

1996 • 54 citations

Valsartan: Long Term Efficacy and Tolerability Compared to Lisinopril in Elderly Patients with Essential Hypertension

1997 • 54 citations

Main results of the losartan versus amlodipine (LOA) study on drug tolerability and psychological general well-being

1997 • 53 citations

Comparative Antihypertensive Effects of Losartan 50 mg and Losartan 50 mg Titrated to 100 mg in Patients with Essential Hypertension

1997 • 52 citations

Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared to hydrochlorothiazide

1997 • 52 citations

Randomised, double-blind, parallel study of the anti-hypertensive efficacy and safety of losartan potassium compared with felodipine ER in elderly patients with mild to moderate hypertension.

1995 • 48 citations

The antihypertensive efficacy of losartan and amlodipine assessed with office and ambulatory blood pressure monitoring. Canadian Cozaar Hyzaar Amlodipine Trial Study Group.

1998 • 48 citations

Clinical Overview of IrbesartanA New Angiotensin II Receptor Antagonist

1997 • 46 citations

Antihypertensive efficacy and tolerability of once daily losartan potassium compared with captopril in patients with mild to moderate essential hypertension

1995 • 37 citations

Dose-finding study of candesartan cilexetil plus hydrochlorothiazide in patients with mild to moderate hypertension.

1997 • 36 citations

Candesartan cilexetil: a new, long-acting, effective angiotensin II type 1 receptor blocker.

1997 • 36 citations

The efficacy and tolerability of candesartan cilexetil in an elderly hypertensive population.

1997 • 35 citations

The Antihypertensive Efficacy of the Combination of Irbesartan and Hydrochlorotfflazide Assessed by 24-Hour Ambulatory Blood Pressure Monitoring

1999 • 33 citations

Losartan potassium lowers blood pressure measured by ambulatory blood pressure monitoring

1995 • 32 citations

D4 Safety and efficacy of irbesartan in hypertensive patients with type II diabetes and proteinuria

1997 • 29 citations

Candesartan cilexetil and enalapril are of equivalent efficacy in patients with mild to moderate hypertension.

1997 • 28 citations

Valsartan, a new angiotensin II antagonist; blood pressure reduction in essential hypertension compared with an angiotensin converting enzyme inhibitor, enalapril.

1997 • 27 citations

Efficacy and Tolerability of Irbesartan, an Angiotensin II Receptor Antagonist, in Primary Hypertension

1998 • 25 citations

Pharmacokinetics and pharmacodynamics of candesartan after administration of its pro-drug candesartan cilexetil in patients with mild to moderate essential hypertension - a population analysis

1997 • 24 citations

A randomized, double-blind comparison of the antihypertensive efficacy and safety of once-daily losartan compared to twice-daily captopril in mild to moderate essential hypertension.

1997 • 20 citations

Clinical overview of irbesartan: expanding the therapeutic window in hypertension.

1997 • 16 citations

Effects of losartan titrated to losartan/hydrochlorothiazide and amlodipine on blood pressure and peripheral capillary microcirculation in patients with mild-to-moderate hypertension

1998 • 15 citations

Clinical profile of the novel angiotensin II type I blocker candesartan cilexetil

1997 • 15 citations

H13 Antihypertensive effects and tolerability of candesartan cilexetil, amlodipine and their combination

1997 • 12 citations

D5 Irbesartan in combination with hydrochlorothiazide in mild-to-moderate hypertension

1997 • 11 citations

Efficacy, safety, and effects on hypertension-associated symptoms of losartan, alone or in combination with hydrochlorothiazide, versus amlodipine in patients with mild-to-moderate hypertension

1998 • 10 citations

H29 Comparison of the efficacy of two angiotensin II antagonists, valsartan and losartan, in essential hypertension

1997 • 9 citations

E056 Combination of candesartan cilexetil/hydrochlorothiazide 8/12.5 mg has a similar antihypertensive effect and is better tolerated than lisinopril/hydrochlorothiazide 10/12.5 mg

1998 • 4 citations

D006 The combination of valsartan and hydrochlorothiazide is effective and well tolerated in essential hypertension

1998 • 4 citations

E046 The angiotensin-II receptor blocker candesartan cilexetil provides 24-hour blood pressure control with once-a-day administration in mild-to-moderate hypertension

1998 • 2 citations

[The first clinical experience in Italy with angiotensin II receptor antagonists: results of a multicenter study on the efficacy and tolerance in arterial hypertension].

1995 • 2 citations