H1N1 influenza A virus-associated acute lung injury: response to combination oseltamivir and prolonged corticosteroid treatment

APACHE II-A Severity of Disease Classification System

1986 • 12,607 citations

APACHE II

1985 • 12,347 citations

Ventilation with Lower Tidal Volumes as Compared with Traditional Tidal Volumes for Acute Lung Injury and the Acute Respiratory Distress Syndrome

2000 • 11,795 citations

The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure

1996 • 9,565 citations

The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination.

1994 • 6,682 citations

Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults

2007 • 5,943 citations

Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008

2007 • 4,077 citations

Effect of Treatment With Low Doses of Hydrocortisone and Fludrocortisone on Mortality in Patients With Septic Shock

2002 • 3,043 citations

Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans

2009 • 2,995 citations

Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs

2005 • 2,909 citations

An Expanded Definition of the Adult Respiratory Distress Syndrome

1988 • 2,636 citations

Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

2006 • 1,803 citations

Critically Ill Patients With 2009 Influenza A(H1N1) Infection in Canada

2009 • 1,435 citations

Pneumonia and Respiratory Failure from Swine-Origin Influenza A (H1N1) in Mexico

2009 • 1,335 citations

SARS: Systematic Review of Treatment Effects

2006 • 1,235 citations

In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses

2009 • 1,067 citations

Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: Consensus statements from an international task force by the American College of Critical Care Medicine

2008 • 877 citations

Critically Ill Patients With 2009 Influenza A(H1N1) in Mexico

2009 • 849 citations

Methylprednisolone Infusion in Early Severe ARDS

2007 • 708 citations

Hydrocortisone Infusion for Severe Community-acquired Pneumonia

2004 • 696 citations

Corticosteroids in the Treatment of Severe Sepsis and Septic Shock in Adults

2009 • 542 citations

Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain

2009 • 460 citations

Use of corticosteroids in acute lung injury and acute respiratory distress syndrome: A systematic review and meta-analysis*

2009 • 353 citations

Intensive-care patients with severe novel influenza A (H1N1) virus infection - Michigan, June 2009.

2009 • 326 citations

Effect of low doses of corticosteroids in septic shock patients with or without early acute respiratory distress syndrome*

2005 • 299 citations

Treatment of Severe Acute Respiratory Syndrome With Glucosteroids

2006 • 275 citations

Prolonged Methylprednisolone Treatment Suppresses Systemic Inflammation in Patients with Unresolving Acute Respiratory Distress Syndrome

2002 • 256 citations

Hospitalized Patients With Novel Influenza A (H1N1) Virus Infection—California, April-May, 2009

2009 • 254 citations

Activation and Regulation of Systemic Inflammation in ARDS

2009 • 239 citations

Screening of ARDS patients using standardized ventilator settings: influence on enrollment in a clinical trial

2004 • 182 citations

Intensive-care patients with severe novel influenza A (H1N1) virus infection - Michigan, June 2009.

2009 • 177 citations

Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature

2007 • 168 citations

Nuclear Factor-ĸB- and Glucocorticoid Receptor α- Mediated Mechanisms in the Regulation of Systemic and Pulmonary Inflammation during Sepsis and Acute Respiratory Distress Syndrome

2005 • 156 citations

Correlations between Lung Proinflammatory Cytokine Levels, Virus Replication, and Disease after Swine Influenza Virus Challenge of Vaccination-Immune Pigs

2002 • 138 citations

Corticosteroid treatment of severe acute respiratory syndrome in Hong Kong

2006 • 103 citations

Medical treatment of viral pneumonia including SARS in immunocompetent adult

2004 • 98 citations

A rationale for using steroids in the treatment of severe cases of H5N1 avian influenza

2007 • 71 citations

Hospitalized patients with novel influenza A (H1N1) virus infection - California, April-May, 2009.

2009 • 42 citations