Low expression of p27 indicates a poor prognosis in patients with high‐grade astrocytomas

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1994 • 2,154 citations

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1994 • 2,071 citations

World Health Organization classification of tumors

2000 • 1,998 citations

Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27

1995 • 1,848 citations

p21 is necessary for the p53-mediated G1 arrest in human cancer cells.

1995 • 1,193 citations

p53-Independent Expression of p21 ^Cip1 in Muscle and Other Terminally Differentiating Cells

1995 • 1,058 citations

p27kip1: A Multifunctional Cyclin-Dependent Kinase Inhibitor with Prognostic Significance in Human Cancers

1999 • 594 citations

Somatic mutations of PTEN in glioblastoma multiforme.

1997 • 526 citations

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G ₁ cell cycle arrest in human glioblastoma cells

1998 • 480 citations

Increased levels of p21WAF1/Cip1 in human brain tumors.

1995 • 159 citations

Expression of p21 (waf1/cip1/sdi1), but not p53 protein, is a factor in the survival of patients with advanced gastric carcinoma

1997 • 128 citations

p21WAF1 immunohistochemical expression in breast carcinoma: correlations with clinicopathological data, oestrogen receptor status, MIB1 expression, p53 gene and protein alterations and relapse-free survival

1996 • 121 citations

p21 expression as a predictor for favorable prognosis in squamous cell carcinoma of the lung.

1997 • 93 citations

Clinical Relevance of Expression of the CIP/KIP Cell-Cycle Inhibitors p21 and p27 in Laryngeal Cancer

1999 • 80 citations

Aberrant p53 expression in astrocytic neoplasms of the brain: association with proliferation.

1993 • 79 citations

p27/kip1 expression in human astrocytic gliomas

1997 • 59 citations

Prognostic value of the expression of tumor suppressor genes p53, p21, p16 and prb, and Ki-67 labelling in high grade astrocytomas treated with radiotherapy.

2000 • 58 citations

Advances in the molecular genetics of gliomas

1997 • 57 citations

p27kip1 immunoreactivity correlates with long-term survival in pleural malignant mesothelioma

2001 • 56 citations

p27^{Kip 1} Expression by Contact Inhibition as a Prognostic Index of Human Glioma

2000 • 51 citations

Immunohistochemical study of p21WAF1 and p53 proteins in prostatic cancer and their prognostic significance

1998 • 42 citations

p27/kip1 expression in oligodendrogliomas and its possible prognostic role

1999 • 30 citations