Construction of a yeast artificial chromosome contig spanning the spinal muscular atrophy disease gene region.

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

1984 • 2,847 citations

A novel, rapid method for the isolation of terminal sequences from yeast artificial chromosome (YAC) clones

1990 • 650 citations

Genetic mapping of chronic childhood-onset spinal muscular atrophy to chromosome 5q1 1.2–13.3

1990 • 579 citations

Alu polymerase chain reaction: a method for rapid isolation of human-specific sequences from complex DNA sources.

1989 • 578 citations

Systematic screening of yeast artificial-chromosome libraries by use of the polymerase chain reaction.

1990 • 454 citations

Exon amplification: a strategy to isolate mammalian genes based on RNA splicing.

1991 • 425 citations

Construction and characterization of a yeast artificial chromosome library containing seven haploid human genome equivalents.

1990 • 408 citations

The Human Y Chromosome: Overlapping DNA Clones Spanning the Euchromatic Region

1992 • 394 citations

Genetic homogeneity between acute and chronic forms of spinal muscular atrophy

1990 • 333 citations

Isolation of Single-Copy Human Genes from a Library of Yeast Artificial Chromosome Clones

1989 • 316 citations

Direct selection: a method for the isolation of cDNAs encoded by large genomic regions.

1991 • 271 citations

Mapping of acute (type I) spinal muscular atrophy to chromosome 5q12-q14

1990 • 247 citations

Direct visualization of single copy genes on banded metaphase chromosomes by nonisotopicin situhybridization

1988 • 110 citations

A Clinical and Genetic Study of Spinal Muscular Atrophy of Adult Onset: The Autosomal Recessive Form as a Discrete Disease Entity

1978 • 72 citations

Characterization of a yeast artificial chromosome contig spanning the Huntington's disease gene candidate region

1992 • 63 citations

Refinement of the Spinal Muscular Atrophy Locus to the Interval between D5S435 and MAP1B

1993 • 63 citations

Mapping of human microtubule-associated protein 1B in proximity to the spinal muscular atrophy locus at 5q13.

1991 • 50 citations

Deletion mapping of DNA markers to a region of chromosome 5 that cosegregates with schizophrenia

1989 • 44 citations

Linkage disequilibrium between two highly polymorphic microsatellites.

1991 • 37 citations

Fine-mapping of the spinal muscular atrophy locus to a region flanked by MAP1B and D5S6

1992 • 29 citations

Combinatoric strategies for genome mapping

1991 • 22 citations

Muscle Disorders in Childhood

1979 • 15 citations

Infantile motor neuron diseases.

1982 • 12 citations