Maximizing the natriuretic effect of endogenous atriopeptin in a rat model of heart failure.

Atrial natriuretic factor in normal subjects and heart failure patients. Plasma levels and renal, hormonal, and hemodynamic responses to peptide infusion.

1986 • 711 citations

Atrial natriuretic factor selectively activates particulate guanylate cyclase and elevates cyclic GMP in rat tissues.

1984 • 676 citations

Atrial Natriuretic Peptide and Atrial Pressure in Patients with Congestive Heart Failure

1986 • 592 citations

Clinical application of atrial natriuretic polypeptide in patients with congestive heart failure: beneficial effects on left ventricular function.

1987 • 344 citations

The hydrolysis of α-human atrial natriuretic peptide by pig kidney microvillar membranes is initiated by endopeptidase-24.11

1987 • 280 citations

Augmented expression of atrial natriuretic polypeptide gene in ventricle of human failing heart.

1989 • 233 citations

Atrial Natriuretic Peptide Inhibits a Cation Channel in Renal Inner Medullary Collecting Duct Cells

1989 • 228 citations

The increase of cGMP by atrial natriuretic factor correlates with the distribution of particulate guanylate cyclase

1985 • 228 citations

HAEMODYNAMIC EFFECTS OF ATRIAL PEPTIDE INFUSION IN HEART FAILURE

1986 • 157 citations

Myocardial recruitment during ANF mRNA increase with volume overload in the rat

1986 • 147 citations

Increased secretion of atrial natriuretic polypeptide from the left ventricle in patients with dilated cardiomyopathy.

1989 • 135 citations

Cyclic GMP as mediator and biological marker of atrial natriuretic factor.

1986 • 124 citations

An immunoradiometric assay for endopeptidase-24.11 shows it to be a widely distributed enzyme in pig tissues

1985 • 118 citations

cGMP mediates effects of atrial peptides on medullary collecting duct cells

1987 • 104 citations

In vivo evidence that cGMP is the second messenger for atrial natriuretic factor.

1986 • 86 citations

Atrial natriuretic factor plays a significant role in body fluid homeostasis.

1990 • 80 citations

Effects of antiallergic agents, compound 48/80, and some reference inhibitors on the activity of partially purified human lung tissue adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate phosphodiesterases.

1977 • 76 citations

Specific inhibitors of endopeptidase 24.11 inhibit the metabolism of atrial natriuretic peptides in vitro and in vivo

1989 • 73 citations

Renal response to atrial natriuretic factor in conscious dogs with caval constriction

1985 • 73 citations

Development, validation and application of an enzyme immunoassay (EIA) of atriopeptin

1987 • 71 citations

Urinary cGMP as biological marker of the renal activity of atrial natriuretic factor

1988 • 69 citations

Hormonal determinants of sodium excretion in rats with experimental high-output heart failure

1988 • 66 citations

Effects of renal perfusion pressure on the natriuresis induced by atrial natriuretic factor

1987 • 50 citations

Thiorphan, an Inhibitor of Endopeptidase 24.11, Potentiates the Natriuretic Activity of Atrial Natriuretic Peptide

1989 • 48 citations

Augmentation of the natriuretic activity of exogenous and endogenous atriopeptin in rats by inhibition of guanosine 3',5'-cyclic monophosphate degradation.

1990 • 48 citations

Inhibition of Jv by ANF in rat proximal straight tubules requires angiotensin

1989 • 46 citations

Renal sympathetic nerves attenuate the natriuretic effects of atrial peptide.

1989 • 34 citations

Attenuated response to atrial natriuretic peptide in rats with myocardial infarction

1989 • 22 citations

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