Irreversible inhibition of S-adenosylhomocysteine hydrolase by nucleoside analogs

The Enzymatic Synthesis of S-Adenosyl-l-homocysteine from Adenosine and Homocysteine

1959 • 546 citations

Some properties of specific cholinesterase with particular reference to the mechanism of inhibition by diethyl p-nitrophenyl thiophosphate (E 605) and analogues

1950 • 475 citations

Enzyme-Activated Irreversible Inhibitors

1979 • 420 citations

Suicide enzyme inactivators

1976 • 366 citations

The mechanism of action of S-adenosylhomocysteinase.

1979 • 347 citations

Apparent suicide inactivation of human lymphoblast S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine and adenine arabinoside. A basis for direct toxic effects of analogs of adenosine.

1979 • 277 citations

Role of S-adenosylhomocysteine in adenosine-mediated toxicity in cultured mouse T lymphoma cells

1977 • 267 citations

S-Adenosyl-L-homocysteine hydrolase: analogues of S-adenosyl-L-homocysteine as potential inhibitors.

1977 • 182 citations

Perturbation of biochemical transmethylations by 3-deazaadenosine in vivo

1979 • 170 citations

Adenosine analogs as substrates and inhibitors of S-adenosylhomocysteine hydrolase

1981 • 157 citations

Adenosylhomocysteine hydrolase. Crystallization of the purified enzyme and its properties.

1978 • 145 citations

3-Deazaadenosine, an inhibitor of adenosylhomocysteine hydrolase, inhibits reproduction of rous sarcoma virus and transformation of chick embryo cells

1978 • 110 citations

Adenosylhomocysteinase from Yellow Lupin Seeds

1977 • 96 citations

Nucleoside Antibiotics

1970 • 76 citations

The action of the adenosylhomocysteine hydrolase inhibitor, 3-deazaadenosine, on phagocytic function of mouse macrophages and human monocytes

1978 • 73 citations

Modulation of Protein Function

1979 • 62 citations

Adenosylhomocysteine hydrolase inhibitors: Synthesis of 5′-deoxy-5′-(isobutylthio)-3-deazaadenosine and its effect on Rous sarcoma virus and Gross murine leukemia virus

1978 • 62 citations

An adenosine 3′:5′‐monophosphate adenosine‐binding protein from mouse liver

1978 • 44 citations

The mechanism of inactivation of S-adenosylhomocysteinase by 2′-deoxyadenosine

1980 • 43 citations

S-Adenosylhomocysteinase from mouse liver. Effect of adenine and adenine nucleotides on the enzyme catalysis

1979 • 43 citations

Biphasic inactivation of procine heart mitochondrial malate dehydrogenase by pyridoxal 5'-phosphate

1975 • 37 citations

Metabolism of S-adenosylhomocysteine and S-tubercidinylhomocysteine in neuroblastoma cells

1979 • 32 citations

Cyclic AMP-adenosine binding protein/S-adenosylhomocysteinase from mouse liver

1979 • 24 citations

Inhibition of nucleoside and sugar transport into cells by an oncostatic methylase inhibitor, 5′‐deoxy‐5′‐S‐isobutyl‐thioadenosine (SIBA)

1979 • 19 citations

Adenosylhomocysteinase:Adenosine complex

1978 • 13 citations