Mass Spectrometric Studies on the Inhibition of TEM-2.BETA.-Lactamase by Clavulanic Acid Derivatives.

Roland P. A. Brown; Robin T. Aplin; Christopher J. Schofield; COLIN H. FRYDRYCH

doi:10.7164/antibiotics.50.184

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Mass Spectrometric Studies on the Inhibition of TEM-2.BETA.-Lactamase by Clavulanic Acid Derivatives.

Roland P. A. Brown, Robin T. Aplin, Christopher J. Schofield, COLIN H. FRYDRYCH

DOI: 10.7164/antibiotics.50.184

The Journal of Antibiotics

Data up to Jan 2025

Published1997

Citations11

References7

Fields

Chemistry Biology Computer science Microbiology Chromatography Stereochemistry

Total Citations Per Year

Abstract

References (7)

Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerus

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Inactivation of class A .beta.-lactamases by clavulanic acid: the role of arginine-244 in a proposed nonconcerted sequence of events

1993 • 135 citations

Inhibition of TEM-2 β-Lactamase from Escherichia coli by Clavulanic Acid: Observation of Intermediates by Electrospray Ionization Mass Spectrometry^,

1996 • 109 citations

Inhibition of β-lactamase by clavulanate

1992 • 98 citations

A semi-synthetic penicillinase inactivator

1979 • 91 citations

The inhibition of staphylococcal β-lactamase by clavulanic acid

1979 • 80 citations

Inactivation of radiolabeled RTEM .beta.-lactamase from Escherichia coli by clavulanic acid and 9-deoxyclavulanic acid

1981 • 67 citations

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