Prevalence of germline truncating mutations inATM in women with a second breast cancer after radiation therapy for a contralateral tumor

A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase

1995 • 2,767 citations

Ataxia telangiectasia: a human mutation with abnormal radiation sensitivity

1975 • 984 citations

Incidence of Cancer in 161 Families Affected by Ataxia–Telangiectasia

1991 • 944 citations

Handbook of Clinical Neurology

1970 • 919 citations

Breast and Other Cancers in Families with Ataxia-Telangiectasia

1987 • 730 citations

ATM Mutations and Phenotypes in Ataxia-Telangiectasia Families in the British Isles: Expression of Mutant ATM and the Risk of Leukemia, Lymphoma, and Breast Cancer

1998 • 403 citations

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

1999 • 371 citations

Heterozygous ATM mutations do not contribute to early onset of breast cancer

1997 • 347 citations

Molecular genotyping shows that ataxia-telangiectasia heterozygotes are predisposed to breast cancer

1996 • 336 citations

Predominance of null mutations in ataxia-telangiectasia

1996 • 293 citations

Cancer Risks in A-T Heterozygotes

1994 • 287 citations

Clustering of missense mutations in the ataxia-telanglectasia gene in a sporadic T-cell leukaemia

1997 • 270 citations

Biallelic mutations in the ATM gene in T-prolymphocytic leukemia

1997 • 266 citations

Ataxia-Telangiectasia: Identification and Detection of Founder-Effect Mutations in the ATM Gene in Ethnic Populations

1998 • 171 citations

Contralateral breast cancer: clinical characteristics and impact on prognosis.

1993 • 158 citations

Inactivation of the ATM Gene in T-Cell Prolymphocytic Leukemias

1998 • 158 citations

The ATM gene and susceptibility to breast cancer: analysis of 38 breast tumors reveals no evidence for mutation.

1996 • 154 citations

Cancer in homozygotes and heterozygotes of ataxia-telangiectasia and xeroderma pigmentosum in Britain.

1988 • 153 citations

Cancer in Ataxia-telangiectasia patients

1990 • 148 citations

Ataxia-telangiectasia: mutations in ATM cDNA detected by protein-truncation screening.

1996 • 144 citations

Inactivation of the ATM Gene in T-Cell Prolymphocytic Leukemias

1998 • 126 citations

A Comparison of the Radiosensitivity of Lymphocytes from Normal Donors, Cancer Patients, Individuals with Ataxia-telangiectasia (A-T) and A-T Heterozygotes

1995 • 110 citations

Mutations Revealed by Sequencing the 5' Half of the Gene for Ataxia Telangiectasia

1996 • 94 citations

Germline mutations in PTEN are an infrequent cause of genetic predisposition to breast cancer

1998 • 70 citations

Heterozygous Germline ATM Mutations Do Not Contribute to Radiation-Associated Malignancies After Hodgkin's Disease

1999 • 68 citations

Dose to contralateral breast: A comparison of four primary breast irradiation techniques

1996 • 60 citations

Detection of heterozygous truncating mutations in the BRCA1 and APC genes by using a rapid screening assay in yeast

1997 • 52 citations