Protein folding for pleasure and for profit

Are there pathways for protein folding?

1968 • 1,496 citations

Specific Intermediates in the Folding Reactions of Small Proteins and the Mechanism of Protein Folding

1982 • 1,041 citations

The purification of eukaryotic polypeptides synthesized in Escherichia coli

1986 • 838 citations

‘Molten‐globule state’: a compact form of globular proteins with mobile side‐chains

1983 • 723 citations

α‐lactalbumin: compact state with fluctuating tertiary structure?

1981 • 611 citations

Experimental studies of protein folding and unfolding

1979 • 535 citations

Biosynthesis of HLA-A and HLA-B antigens in vivo.

1980 • 253 citations

Tumour necrosis factor is a compact trimer

1987 • 136 citations

Effects of the phenylalanine-22 .fwdarw. leucine, glutamic acid-49 .fwdarw. methionine, glycine-234 .fwdarw. aspartic acid and glycine-234 .fwdarw. lysine mutations on the folding and stability of the .alpha. subunit of tryptophan synthase from Escherichia coli

1986 • 99 citations

The formation of the tertiary structure of proteins.

1967 • 90 citations

Seeding protein folding

1986 • 77 citations

Effects of sulphate and urea on the stability and reversible unfolding of β-lactamase from Staphylococcus aureus

1985 • 76 citations

Single amino acid mutations block a late step in the folding of β-lactamase from Staphylococcus aureus

1985 • 62 citations

An artificial crystalline DDT‐binding polypeptide

1983 • 57 citations

Genetic Analysis of Protein Folding Pathways

1986 • 52 citations

Production of native, correctly folded bovine pancreatic trypsin inhibitor by Escherichia coli.

1986 • 52 citations