A dopaminergic neurotoxin, (R)‐N‐methylsalsolinol, increases in parkinsonian cerebrospinal fluid

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

1983 • 4,822 citations

Advances in Our Understanding of the Mechanisms of the Neurotoxicity of MPTP and Related Compounds

1993 • 541 citations

Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies

1996 • 127 citations

N‐Methylation of Dopamine‐Derived 6,7‐Dihydroxy‐1,2,3,4‐Tetrahydroisoquinoline, (R)‐Salsolinol, in Rat Brains: In Vivo Microdialysis Study

1992 • 102 citations

Uptake of a neurotoxin-candidate, (R)-1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline into human dopaminergic neuroblastoma SH-SY5Y cells by dopamine transport system

1994 • 99 citations

N-methyl(r)salsolinol produces hydroxyl radicals: Involvement to neurotoxicity

1995 • 97 citations

Presence of 2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline and 1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, novel endogenous amines, in parkinsonian and normal human brains

1991 • 96 citations

Ratio of the R and S enantiomers of salsolinol in food and human urine

1989 • 70 citations

Dopamine‐Derived 1‐Methyl‐6,7‐Dihydroxyisoquinolines as Hydroxyl Radical Promoters and Scavengers in the Rat Brain: In Vivo and In Vitro Studies

1995 • 60 citations

Determination of the (R)- and (S)-enantiomers of salsolinol and N-methylsalsolinol by use of a chiral high-performance liquid chromatographic column

1995 • 54 citations

Enzymatic oxidation of the dopaminergic neurotoxin, 1 (R), 2(N)-Dimethyl-6,7-Dihydroxy-l,2,3,4-Tetrahydroisoquinoline, into 1,2(N)-Dimethyl-6,7-Dihydroxyisoquinolinium ion

1995 • 48 citations

Enantiomeric composition of urinary salsolinol in Parkinsonian patients after Madopar

1989 • 43 citations

Binding of 1,2(N)-dimethyl-6,7-dihydroxy-isoquinolinium ion to melanin: Effects of ferrous and ferric ion on the binding

1994 • 27 citations

Multi-electrode detection systems for determination of neurotransmitters

1993 • 11 citations