Disposition of the neuroleptic zuclopenthixol cosegregates with the polymorphic hydroxylation of debrisoquine in humans

POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN

1977 • 1,196 citations

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

1988 • 717 citations

Defective N-oxidation of sparteine in man: A new pharmacogenetic defect

1979 • 647 citations

Significance of Neuroleptic Dose and Plasma Level in the Pharmacological Treatment of Psychoses

1988 • 554 citations

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

1980 • 544 citations

Clinical significance of the sparteine/debrisoquine oxidation polymorphism

1989 • 292 citations

Disposition of perphenazine is related to polymorphic debrisoquin hydroxylation in luman beings

1989 • 167 citations

Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man

1988 • 152 citations

Polymorphic debrisoquin hydroxylation in 757 Swedish subjects

1988 • 135 citations

A family study of genetic and environmental factors determining polymorphic hydroxylation of debrisoquin

1985 • 127 citations

Active Metabolites of Neuroleptic Drugs

1982 • 76 citations

Dose-response relationships of perphenazine in the treatment of acute psychoses

1982 • 66 citations

Plasma levels of perphenazine (Trilafon) related to development of extrapyramidal side effects

1981 • 51 citations

Serum concentrations and clinical effect of zuclopenthixol in acutely disturbed, psychotic patients treated with zuclopenthixol acetate in Viscoleo�

1986 • 40 citations

Plasma concentrations of perphenazine and its sulphoxide metabolite during continuous oral treatment

1977 • 38 citations

The relationship between blood perphenazine levels, early resolution of psychotic symptoms, and side effects.

1990 • 23 citations

Serum levels of the isomers of clopenthixol in patients given cis(Z)‐clopenthixol or cis(Z)/trans(E)‐clopenthixol

1981 • 18 citations

Zuclopenthixol decanoate in schizophrenia: Serum levels and clinical state

1985 • 12 citations

Manibehandling med cis(Z)-clopenthixol (Cisordinol^R, Clopixol^R)

1982 • 10 citations

Relationer mellem kliniske effekter og plasmakoncentration af perfenazin

1984 • 3 citations

Perfenazin decanoat og flupentixol decanoat i langtidsbehandling Serumniveau ved laveste effektive dosis

1990 • 2 citations